Full Name: Inter-Alpha-Trypsin Inhibitor Heavy Chain 2
BACKGROUND: The inter-alpha-trypsin inhibitors (ITI) are a family of structurally related plasma serine protease inhibitors involved in extracellular matrix stabilization and in prevention of tumor metastasis. The ITI family contains multiple proteins made up of a light chain (see MIM 176870) and a variable number of heavy chains (Salier et al., 1987[PubMed 2446322]; Himmelfarb et al., 2004[PubMed 14744536]).
Synonyms: H2P; SHAP
Research Areas: Cell Biology
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