Full Name: Hydroxysteroid 17-Beta Dehydrogenase 3
BACKGROUND: This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia.
Synonyms: EDH17B3; SDR12C2
Research Areas: Signal Transduction
Pathways: Signal Transduction Pathway
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