HLA-A2

Full Name: Human leukocyte antigen A

BACKGROUND: HLA-A2 (Human Leukocyte Antigen-A2) is one of the most common and well-studied alleles of the HLA-A gene, which is part of the MHC class I family. HLA-A2 molecules present endogenous antigens (from inside the cell) to cytotoxic T lymphocytes (CTLs), playing a critical role in the immune surveillance of viral infections and cancer.

Synonyms: HLA-A; Human leukocyte antigen A; HLA class I histocompatibility antigen; A-2 alpha chain; MHC class I antigen A-2 HLA-A; HLA class I histocompatibility antigen A-28 alpha chain; HLA class I histocompatibility antigen; A-28 alpha chain; MHC class I antigen A-28