Full Name: Cytokine Receptor Like Factor 1
BACKGROUND: This gene encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. The complex can promote survival of neuronal cells. Mutations in this gene result in Crisponi syndrome and cold-induced sweating syndrome.
Synonyms: CISS; CISS1; CLF; CLF-1; NR6; zcytor5
Research Areas: Immunology
Pathways: Immunology Pathway
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