Full Name: Autophagy Related 16 Like 1
BACKGROUND: The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.
Synonyms: APG16L; ATG16A; ATG16L; IBD10; WDR30
Research Areas: Cell Biology
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