Full Name: Activating Signal Cointegrator 1 Complex Subunit 3
BACKGROUND: This gene encodes a protein that belongs to a family of helicases that are involved in the ATP-dependent unwinding of nucleic acid duplexes. The encoded protein is the largest subunit of the activating signal cointegrator 1 complex that is involved in DNA repair and resistance to alkylation damage. Alternate splicing results in multiple transcript variants.
Synonyms: ASC1p200; HELIC1; RNAH
Research Areas: Epigenetics
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