Anti-Z-DNA Monoclonal Antibody (Z22)

Anti-Z-DNA Monoclonal Antibody (Z22)

Cat No: ASPC044

Summary
Host Species:
Mouse
Species Reactivity:
Species independent
Applications:
Surface Plasmon Resonance, Enzyme-Linked Immunosorbent Assay, Western Blot, Flow Cytometry, Immunofluorescence, Immunohistochemistry
Clone ID:
Z22
Clonality:
Monoclonal

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Product Information
Subcat Description Isotype Antibody Modification Conjugate Size Price Availability Quantity
ASPC044 Anti-Z-DNA Antibody (Z22) Mouse IgG2b, Kappa None $460 In stock
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ASPC044-P Anti-Z-DNA Antibody (Z22), PE Mouse IgG2b, Kappa PE $1,180 2-3 weeks
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ASPC044-A Anti-Z-DNA Antibody (Z22), APC Mouse IgG2b, Kappa APC $980 2-3 weeks
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ASPC044-H Anti-Z-DNA Antibody (Z22), HRP Mouse IgG2b, Kappa HRP $600 2-3 weeks
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ASPC044-B Anti-Z-DNA Antibody (Z22), Biotin Mouse IgG2b, Kappa Biotin $680 2-3 weeks
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ASPC044-4 Anti-Z-DNA Antibody (Z22), Fc Silenced Mouse IgG2b, Kappa Fc Silenced None $980 4-6 weeks
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Custom Antibody We can also offer conjugation antibodies (Alexa Fluor, Cy, APC, etc.) and other format antibodies (low endotoxin, Fab, scFv, etc.)

  • Anti-Z-DNA Monoclonal Antibody (Z22)
    • Product Description:
      Z22 is highly specific to Z-DNA, a left-handed double helical structure that is distinct from the right-handed B-DNA, the most common DNA conformation. Z-DNA is typically formed transiently in regions of DNA under torsional stress, such as during transcription.
      Z22 also binds to Z-RNA, a similarly left-handed structure, though less common, that can form under certain conditions in RNA sequences.
      Applications:
      Surface Plasmon Resonance, Enzyme-Linked Immunosorbent Assay, Western Blot, Flow Cytometry, Immunofluorescence, Immunohistochemistry
      Source:
      Mouse
      Target:
      Z-DNA
      Specificity:
      Z-DNA and Z-RNA structures
      Immunogen:
      Brominated poly(dG-dC).poly(dG-dC) complexed with methylated BSA.
      Clonality:
      Monoclonal
      Clone ID:
      Z22
      Isotype:
      Mouse IgG2b, Kappa
      Purification:
      The antibody was purified by Protein A.
      Purity:
      >95% as determined by SDS-PAGE
      Aggregation:
      <5% as determined by SEC
      Concentration:
      1 mg/mL
      Form:
      Liquid
      Endotoxin:
      Please contact us for more information.
      Formulation:
      Contact us for customized product form or formulation.
      Preservative:
      BSA and Azide free.
      Stabilizer:
      None
      Shipping:
      Shipped at 4°C.
      Storage:
      This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
  • Anti-Z-DNA Monoclonal Antibody (Z22) Applications
    • Note:
      Optimal dilutions/concentrations should be determined by the end user.
Introduction
Z-DNA is one of the many possible double helical structures of DNA. It is a left-handed double helical structure in which the helix winds to the left in a zigzag pattern, instead of to the right, like the more common B-DNA form. Z-DNA is thought to be one of three biologically active double-helical structures along with A-DNA and B-DNA.
Alternative Names
DNA; Z-DNA
Cell Type
Astrocytes
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