Anti-WT1 Monoclonal Antibody (15A1)

Anti-WT1 Monoclonal Antibody (15A1)

Cat No: ASPC234

Summary
Host Species:
Human
Species Reactivity:
Human
Applications:
Flow Cytometry, Cytotoxicity Assay, Functional Assay, Immunoblotting
Clone ID:
15A1
Clonality:
Monoclonal

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Product Information
Subcat Description Isotype Antibody Modification Conjugate Size Price Availability Quantity
ASPC234 Anti-WT1 Antibody (15A1) Human IgG1, Lambda None $460 In stock
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ASPC234-P Anti-WT1 Antibody (15A1), PE Human IgG1, Lambda PE $1,180 2-3 weeks
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ASPC234-A Anti-WT1 Antibody (15A1), APC Human IgG1, Lambda APC $980 2-3 weeks
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ASPC234-H Anti-WT1 Antibody (15A1), HRP Human IgG1, Lambda HRP $600 2-3 weeks
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ASPC234-B Anti-WT1 Antibody (15A1), Biotin Human IgG1, Lambda Biotin $680 2-3 weeks
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Custom Antibody We can also offer conjugation antibodies (Alexa Fluor, Cy, APC, etc.) and other format antibodies (low endotoxin, Fab, scFv, etc.)

  • Anti-WT1 Monoclonal Antibody (15A1)
    • Product Description:
      The Anti-WT1 antibody is a human monoclonal antibody recommended for use in flow cytometry, cytotoxicity assay, functional assay, Immunoblotting and other applications. This antibody specifically targets WT1 and demonstrates reactivity with human.
      Applications:
      Flow Cytometry, Cytotoxicity Assay, Functional Assay, Immunoblotting
      Target:
      WT1
      Target Species:
      Human
      Specificity:
      This antibody reacts with human WT1.
      Immunogen:
      Human WT1 protein
      Clonality:
      Monoclonal
      Clone ID:
      15A1
      Purification:
      The antibody was purified by affinity chromatography.
      Purity:
      >95% as determined by SDS-PAGE
      Aggregation:
      <5% as determined by SEC
      Form:
      Liquid
      Endotoxin:
      Please contact us for more information.
      Formulation:
      Contact us for custom product formulation.
      Preservative:
      BSA and Azide free.
      Stabilizer:
      None
      Shipping:
      Shipped at 4°C.
      Storage:
      This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
  • Anti-WT1 Monoclonal Antibody (15A1) Applications
    • Note:
      Optimal dilutions/concentrations should be determined by the end user.
Gene Symbol
WT1
Protein Name
Wilms tumor protein
Introduction
This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilms tumor. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation codon upstream of, and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated.
Alternative Names
GUD; AWT1; WAGR; WT33; NPHS4; WIT-2; EWS-WT1
Gene ID
UniProt
Related Disease
Frasier syndrome (FS)
Subcellular Location
Nucleus
Tissue Specificity
Expressed in the kidney and a subset of hematopoietic cells.
Cell Line Specificity
Cancer enhanced
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