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Anti-WNT7A Monoclonal Antibody (G-10H12)
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Product Description:The Anti-WNT7A antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human WNT7A.Applications:Immunohistochemistry, Immunocytochemistry, Western Blot, ImmunoprecipitationSource:MouseTarget:WNT7ATarget Species:HumanSpecificity:This antibody reacts with human Wnt Family Member 7A (WNT7A).Clonality:MonoclonalClone ID:G-10H12Purification:The antibody was purified by affinity chromatography.Purity:>95% as determined by SDS-PAGEConcentration:1 mg/mLForm:LiquidFormulation:Contact us for custom product formulation.Preservative:0.02% sodium azideShipping:Shipped at 4°C.Storage:This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
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Anti-WNT7A Monoclonal Antibody (G-10H12) Applications
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Recommended Dilution:Western Blot: 1:500-1:5000
Immunohistochemistry: 1:50-1:200
Immunocytochemistry: 1:50-1:200Note:Optimal dilutions/concentrations should be determined by the end user.
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Protein Name
Protein Wnt-7a
Introduction
This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is involved in the development of the anterior-posterior axis in the female reproductive tract, and also plays a critical role in uterine smooth muscle pattering and maintenance of adult uterine function. Mutations in this gene are associated with Fuhrmann and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndromes.
Alternative Names
Wnt Family Member 7A; Wingless-Type MMTV Integration Site Family, Member 7A; Proto-Oncogene Wnt7a Protein
Gene ID
UniProt
Related Disease
Limb pelvis hypoplasia aplasia syndrome (LPHAS)
Subcellular Location
Secreted, extracellular space, extracellular matrix
Tissue Specificity
Expression is restricted to placenta, kidney, testis, uterus, fetal lung, and fetal and adult brain.
Cell Line Specificity
Cancer enhanced
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