Anti-WFDC2 Monoclonal Antibody (H-7H10)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Size	Price	Quantity
ASZ1C1968	Anti-WFDC2 Antibody (H-7H10)	Mouse IgG		None		$460		Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASZ1C1968

Anti-WFDC2 Antibody (H-7H10)

Mouse IgG

None

$460

Add

Anti-WFDC2 Monoclonal Antibody (H-7H10)
- Product Description:
  
  The Anti-WFDC2 antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human WFDC2.
  
  Applications:
  
  Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
  
  Source:
  
  Mouse
  
  Target:
  
  WFDC2
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human WAP Four-Disulfide Core Domain 2 (WFDC2).
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  H-7H10
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  0.02% sodium azide
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-WFDC2 Monoclonal Antibody (H-7H10) Applications
- Recommended Dilution:
  
  Western Blot: 1:500-1:5000
  Immunohistochemistry: 1:50-1:200
  Immunocytochemistry: 1:50-1:200
  
  Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Protein Name

WAP four-disulfide core domain protein 2

Introduction

This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation.

Alternative Names

EDDM4; HE4; WAP5; dJ461P17.6

Gene ID

10406

UniProt

Q14508

Related Disease

Bronchiectasis and nasal polyposis (BENP)

Subcellular Location

Secreted

Tissue Specificity

Expressed in a number of normal tissues, including male reproductive system, regions of the respiratory tract and nasopharynx. Highly expressed in a number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines. Initially described as being exclusively transcribed in the epididymis.

Cell Line Specificity

Cancer enhanced

Function

Broad range protease inhibitor.

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