Anti-VWF Monoclonal Antibody (NMC-4)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC112	Anti-VWF Antibody (NMC-4)	Mouse IgG1, Kappa	None	$460	In stock	Add
ASPC112-P	Anti-VWF Antibody (NMC-4), PE	Mouse IgG1, Kappa	PE	$1,180	2-3 weeks	Add
ASPC112-A	Anti-VWF Antibody (NMC-4), APC	Mouse IgG1, Kappa	APC	$980	2-3 weeks	Add
ASPC112-H	Anti-VWF Antibody (NMC-4), HRP	Mouse IgG1, Kappa	HRP	$600	2-3 weeks	Add
ASPC112-B	Anti-VWF Antibody (NMC-4), Biotin	Mouse IgG1, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC112

Anti-VWF Antibody (NMC-4)

Mouse IgG1, Kappa

None

$460

In stock

Add

ASPC112-P

Anti-VWF Antibody (NMC-4), PE

Mouse IgG1, Kappa

$1,180

2-3 weeks

Add

ASPC112-A

Anti-VWF Antibody (NMC-4), APC

Mouse IgG1, Kappa

APC

$980

2-3 weeks

Add

ASPC112-H

Anti-VWF Antibody (NMC-4), HRP

Mouse IgG1, Kappa

HRP

$600

2-3 weeks

Add

ASPC112-B

Anti-VWF Antibody (NMC-4), Biotin

Mouse IgG1, Kappa

Biotin

$680

2-3 weeks

Add

Anti-VWF Monoclonal Antibody (NMC-4)
- Product Description:
  
  NMC-4 is a mouse monoclonal antibody that recognizes the A1 domain of von Willebrand factor (vWF).
  
  Applications:
  
  Inhibition, Immunoprecipitation, Enzyme-Linked Immunosorbent Assay
  
  Source:
  
  Mouse
  
  Target:
  
  VWF
  
  Target Species:
  
  Human
  
  Specificity:
  
  Human von Willebrand factor
  
  Immunogen:
  
  Human FVIII/vWF fraction
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  NMC-4
  
  Isotype:
  
  Mouse IgG1, Kappa
  
  Purification:
  
  The antibody was purified by Protein A.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for customized product form or formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-VWF Monoclonal Antibody (NMC-4) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

VWF

Protein Name

von Willebrand factor

Introduction

This gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome 22.

Alternative Names

Von Willebrand Factor; F8VWF; Coagulation Factor VIII VWF; VWD; VWF

Gene ID

7450

UniProt

P04275

Related Disease

von Willebrand disease 1 (VWD1)

Tissue Specificity

Plasma.

Cell Type

Platelets

Function

Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.

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