Anti-VWF Monoclonal Antibody (5A10)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC655	Anti-VWF Antibody (5A10)	Mouse IgG2a, Kappa	None	$460	In stock	Add
ASPC655-P	Anti-VWF Antibody (5A10), PE	Mouse IgG2a, Kappa	PE	$1,180	2-3 weeks	Add
ASPC655-A	Anti-VWF Antibody (5A10), APC	Mouse IgG2a, Kappa	APC	$980	2-3 weeks	Add
ASPC655-H	Anti-VWF Antibody (5A10), HRP	Mouse IgG2a, Kappa	HRP	$600	2-3 weeks	Add
ASPC655-B	Anti-VWF Antibody (5A10), Biotin	Mouse IgG2a, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC655

Anti-VWF Antibody (5A10)

Mouse IgG2a, Kappa

None

$460

In stock

Add

ASPC655-P

Anti-VWF Antibody (5A10), PE

Mouse IgG2a, Kappa

$1,180

2-3 weeks

Add

ASPC655-A

Anti-VWF Antibody (5A10), APC

Mouse IgG2a, Kappa

APC

$980

2-3 weeks

Add

ASPC655-H

Anti-VWF Antibody (5A10), HRP

Mouse IgG2a, Kappa

HRP

$600

2-3 weeks

Add

ASPC655-B

Anti-VWF Antibody (5A10), Biotin

Mouse IgG2a, Kappa

Biotin

$680

2-3 weeks

Add

Anti-VWF Monoclonal Antibody (5A10)
- Product Description:
  
  The Anti-VWF antibody is a mouse monoclonal antibody recommended for use in ELISA, functional assay and other applications. This antibody specifically targets VWF and demonstrates reactivity with human, monkey.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Functional Assay
  
  Target:
  
  VWF
  
  Specificity:
  
  This antibody reacts with human VWF.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  5A10
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-VWF Monoclonal Antibody (5A10) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

VWF

Protein Name

von Willebrand factor

Introduction

This gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome 22.

Alternative Names

Von Willebrand Factor; F8VWF; Coagulation Factor VIII VWF; VWD; VWF

Gene ID

7450

UniProt

P04275

Related Disease

von Willebrand disease 1 (VWD1)

Subcellular Location

Secreted

Tissue Specificity

Plasma.

Cell Line Specificity

Low cancer specificity

Function

Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.

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