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Anti-VAMP2 Monoclonal Antibody (B-4D6)
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Product Description:The Anti-VAMP2 antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human VAMP2.Applications:Immunohistochemistry, Immunocytochemistry, Western Blot, ImmunoprecipitationSource:MouseTarget:VAMP2Target Species:HumanSpecificity:This antibody reacts with human Vesicle Associated Membrane Protein 2 (VAMP2).Clonality:MonoclonalClone ID:B-4D6Purification:The antibody was purified by affinity chromatography.Purity:>95% as determined by SDS-PAGEConcentration:1 mg/mLForm:LiquidFormulation:Contact us for custom product formulation.Preservative:0.02% sodium azideShipping:Shipped at 4°C.Storage:This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
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Anti-VAMP2 Monoclonal Antibody (B-4D6) Applications
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Recommended Dilution:Western Blot: 1:500-1:5000
Immunohistochemistry: 1:50-1:200
Immunocytochemistry: 1:50-1:200Note:Optimal dilutions/concentrations should be determined by the end user.
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Protein Name
Vesicle-associated membrane protein 2
Introduction
The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG.
Alternative Names
SYB2; VAMP-2
Gene ID
UniProt
Related Disease
Neurodevelopmental disorder with hypotonia and autistic features with or without hyperkinetic movements (NEDHAHM)
Subcellular Location
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane
Tissue Specificity
Nervous system and skeletal muscle.
Cell Line Specificity
Low cancer specificity
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