Anti-UGGT1 Monoclonal Antibody (D-11B9)

Anti-UGGT1 Monoclonal Antibody (D-11B9)

Cat No: ASZ1C1936

Summary
Host Species:
Mouse
Species Reactivity:
Human
Applications:
Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
Clone ID:
D-11B9
Clonality:
Monoclonal

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Product Information
Subcat Description Isotype Antibody Modification Conjugate Size Price Quantity
ASZ1C1936 Anti-UGGT1 Antibody (D-11B9) Mouse IgG None $460
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  • Anti-UGGT1 Monoclonal Antibody (D-11B9)
    • Product Description:
      The Anti-UGGT1 antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human UGGT1.
      Applications:
      Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
      Source:
      Mouse
      Target:
      UGGT1
      Target Species:
      Human
      Specificity:
      This antibody reacts with human UDP-Glucose Glycoprotein Glucosyltransferase 1 (UGGT1).
      Clonality:
      Monoclonal
      Clone ID:
      D-11B9
      Purification:
      The antibody was purified by affinity chromatography.
      Purity:
      >95% as determined by SDS-PAGE
      Concentration:
      1 mg/mL
      Form:
      Liquid
      Formulation:
      Contact us for custom product formulation.
      Preservative:
      0.02% sodium azide
      Shipping:
      Shipped at 4°C.
      Storage:
      This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
  • Anti-UGGT1 Monoclonal Antibody (D-11B9) Applications
    • Recommended Dilution:
      Western Blot: 1:500-1:5000
      Immunohistochemistry: 1:50-1:200
      Immunocytochemistry: 1:50-1:200
      Note:
      Optimal dilutions/concentrations should be determined by the end user.
Protein Name
UDP-glucose:glycoprotein glucosyltransferase 1
Introduction
UDP-glucose:glycoprotein glucosyltransferase (UGT) is a soluble protein of the endoplasmic reticulum (ER) that selectively reglucosylates unfolded glycoproteins, thus providing quality control for protein transport out of the ER.
Alternative Names
HUGT1; UGCGL1; UGT1
Gene ID
UniProt
Subcellular Location
Endoplasmic reticulum lumen
Tissue Specificity
Higher levels in pancreas, skeletal muscle, kidney, and brain. Low levels in lung and heart.
Cell Line Specificity
Low cancer specificity
Function
Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.
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