Anti-UCN3 Monoclonal Antibody (D-10F11)

Anti-UCN3 Monoclonal Antibody (D-10F11)

Cat No: ASZ1C1934

Summary
Host Species:
Mouse
Species Reactivity:
Human
Applications:
Western Blot
Clone ID:
D-10F11
Clonality:
Monoclonal

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Product Information
Subcat Description Isotype Antibody Modification Conjugate Size Price Quantity
ASZ1C1934 Anti-UCN3 Antibody (D-10F11) Mouse IgG2b, Kappa None $460
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  • Anti-UCN3 Monoclonal Antibody (D-10F11)
    • Product Description:
      The Anti-UCN3 antibody is a mouse monoclonal antibody recommended for western blot and other applications. This antibody specifically targets human UCN3.
      Applications:
      Western Blot
      Source:
      Mouse
      Target:
      UCN3
      Target Species:
      Human
      Specificity:
      This antibody reacts with human Urocortin 3 (UCN3).
      Immunogen:
      Recombinant UCN3 protein
      Clonality:
      Monoclonal
      Clone ID:
      D-10F11
      Purification:
      The antibody was purified by affinity chromatography.
      Purity:
      >95% as determined by SDS-PAGE
      Concentration:
      1 mg/mL
      Form:
      Liquid
      Formulation:
      Contact us for custom product formulation.
      Preservative:
      0.05% Proclin 300
      Shipping:
      Shipped at 4°C.
      Storage:
      This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
  • Anti-UCN3 Monoclonal Antibody (D-10F11) Applications
    • Recommended Dilution:
      Western Blot: 0.01-2 µg/mL
      Note:
      Optimal dilutions/concentrations should be determined by the end user.
Protein Name
Urocortin-3
Introduction
This gene encodes a member of the sauvagine/corticotropin-releasing factor/urotensin I family of proteins. The encoded preproprotein is proteolytically processed to generate the mature peptide hormone, which is secreted by pancreatic beta and alpha cells. This hormone is an endogenous ligand for corticotropin-releasing factor receptor 2 and may regulate insulin secretion in response to plasma glucose levels. Patients with type 2 diabetes exhibit reduced levels of the encoded protein in beta cells. In the brain, the encoded protein may be responsible for the effects of stress on appetite.
Alternative Names
SCP; SPC; UCNIII
Gene ID
UniProt
Subcellular Location
Secreted.
Cell Line Specificity
Group enriched
Function
Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.
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