Anti-UBE2L3 Monoclonal Antibody (A-16F12)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Size	Price	Quantity
ASZ1C1929	Anti-UBE2L3 Antibody (A-16F12)	Mouse IgG		None		$460		Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASZ1C1929

Anti-UBE2L3 Antibody (A-16F12)

Mouse IgG

None

$460

Add

Anti-UBE2L3 Monoclonal Antibody (A-16F12)
- Product Description:
  
  The Anti-UBE2L3 antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human UBE2L3.
  
  Applications:
  
  Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
  
  Source:
  
  Mouse
  
  Target:
  
  UBE2L3
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human Ubiquitin Conjugating Enzyme E2 L3 (UBE2L3).
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  A-16F12
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  0.02% sodium azide
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-UBE2L3 Monoclonal Antibody (A-16F12) Applications
- Recommended Dilution:
  
  Western Blot: 1:500-1:5000
  Immunohistochemistry: 1:50-1:200
  Immunocytochemistry: 1:50-1:200
  
  Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Protein Name

Ubiquitin-conjugating enzyme E2 L3

Introduction

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene.

Alternative Names

E2-F1; L-UBC; UBCH7; UbcM4

Gene ID

7332

UniProt

P68036

Subcellular Location

Nucleus

Tissue Specificity

Ubiquitous, with highest expression in testis.

Cell Line Specificity

Low cancer specificity