Anti-UBE2A Monoclonal Antibody (C-7D10)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Size	Price	Quantity
ASZ1C1926	Anti-UBE2A Antibody (C-7D10)	Mouse IgG		None		$460		Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASZ1C1926

Anti-UBE2A Antibody (C-7D10)

Mouse IgG

None

$460

Add

Anti-UBE2A Monoclonal Antibody (C-7D10)
- Product Description:
  
  The Anti-UBE2A antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human UBE2A.
  
  Applications:
  
  Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
  
  Source:
  
  Mouse
  
  Target:
  
  UBE2A
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human Ubiquitin Conjugating Enzyme E2 A (UBE2A).
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  C-7D10
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  0.02% sodium azide
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-UBE2A Monoclonal Antibody (C-7D10) Applications
- Recommended Dilution:
  
  Western Blot: 1:500-1:5000
  Immunohistochemistry: 1:50-1:200
  Immunocytochemistry: 1:50-1:200
  
  Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Protein Name

Ubiquitin-conjugating enzyme E2 A

Introduction

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair, and may play a role in transcriptional regulation. Mutations in this gene are associated with cognitive disability. Alternative splicing results in multiple transcript variants.

Alternative Names

HHR6A; MRXS30; MRXSN; RAD6A; UBC2

Gene ID

7319

UniProt

P49459

Related Disease

Intellectual developmental disorder, X-linked, syndromic, Nascimento-type (MRXSN)

Subcellular Location

Late endosome

Cell Line Specificity

Low cancer specificity