Anti-TRPC6 Monoclonal Antibody (D-3E9)

Anti-TRPC6 Monoclonal Antibody (D-3E9)

Cat No: ASZ1C1898

Summary
Host Species:
Mouse
Species Reactivity:
Human
Applications:
Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
Clone ID:
D-3E9
Clonality:
Monoclonal

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Product Information
Subcat Description Isotype Antibody Modification Conjugate Size Price Quantity
ASZ1C1898 Anti-TRPC6 Antibody (D-3E9) Mouse IgG None $460
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  • Anti-TRPC6 Monoclonal Antibody (D-3E9)
    • Product Description:
      The Anti-TRPC6 antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human TRPC6.
      Applications:
      Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
      Source:
      Mouse
      Target:
      TRPC6
      Target Species:
      Human
      Specificity:
      This antibody reacts with human Transient Receptor Potential Cation Channel Subfamily C Member 6 (TRPC6).
      Clonality:
      Monoclonal
      Clone ID:
      D-3E9
      Purification:
      The antibody was purified by affinity chromatography.
      Purity:
      >95% as determined by SDS-PAGE
      Concentration:
      1 mg/mL
      Form:
      Liquid
      Formulation:
      Contact us for custom product formulation.
      Preservative:
      0.02% sodium azide
      Shipping:
      Shipped at 4°C.
      Storage:
      This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
  • Anti-TRPC6 Monoclonal Antibody (D-3E9) Applications
    • Recommended Dilution:
      Western Blot: 1:500-1:5000
      Immunohistochemistry: 1:50-1:200
      Immunocytochemistry: 1:50-1:200
      Note:
      Optimal dilutions/concentrations should be determined by the end user.
Protein Name
Short transient receptor potential channel 6
Introduction
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).
Alternative Names
FSGS2; TRP6
Gene ID
UniProt
Related Disease
Focal segmental glomerulosclerosis 2 (FSGS2)
Subcellular Location
Cell membrane
Tissue Specificity
Expressed primarily in placenta, lung, spleen, ovary and small intestine. Expressed in podocytes and is a component of the glomerular slit diaphragm.
Cell Line Specificity
Cancer enhanced
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