Anti-TP53 Monoclonal Antibody - Amerigo Scientific

Subcat	Description	Isotype	Conjugate	Price
ASPC1396	Anti-TP53 Antibody	Mouse IgG2a, Kappa	None	$460	Add
ASPC1396-A	Anti-TP53 Antibody, APC	Mouse IgG2a, Kappa	APC	$980	Add
ASPC1396-B	Anti-TP53 Antibody, Biotin	Mouse IgG2a, Kappa	Biotin	$680	Add
ASPC1396-H	Anti-TP53 Antibody, HRP	Mouse IgG2a, Kappa	HRP	$600	Add
ASPC1396-P	Anti-TP53 Antibody, PE	Mouse IgG2a, Kappa	PE	$1,180	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC1396

Anti-TP53 Antibody

Mouse IgG2a, Kappa

None

$460

Add

ASPC1396-A

Anti-TP53 Antibody, APC

Mouse IgG2a, Kappa

APC

$980

Add

ASPC1396-B

Anti-TP53 Antibody, Biotin

Mouse IgG2a, Kappa

Biotin

$680

Add

ASPC1396-H

Anti-TP53 Antibody, HRP

Mouse IgG2a, Kappa

HRP

$600

Add

ASPC1396-P

Anti-TP53 Antibody, PE

Mouse IgG2a, Kappa

$1,180

Add

Anti-TP53 Monoclonal Antibody
- Product Description:
  
  The Anti-TP53 antibody is a mouse monoclonal antibody recommended for use in immunohistochemistry, enzyme-linked immunosorbent assay, western blot and other applications. This antibody specifically targets TP53 and demonstrates reactivity with human.
  
  Applications:
  
  Immunohistochemistry, Enzyme-Linked Immunosorbent Assay, Western Blot
  
  Source:
  
  Mouse
  
  Target:
  
  TP53
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with Human TP53.
  
  Immunogen:
  
  Recombinant human p53.
  
  Clonality:
  
  Monoclonal
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-TP53 Monoclonal Antibody Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

TP53

Protein Name

Cellular tumor antigen p53

Introduction

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277).

Alternative Names

BCC7; LFS1; P53; TRP53

Gene ID

7157

UniProt

P04637

Subcellular Location

Cytoplasm

Tissue Specificity

Ubiquitous. Isoforms are expressed in a wide range of normal tissues but in a tissue-dependent manner.

Cell Line Specificity

Low cancer specificity