Anti-TNFRSF9 Monoclonal Antibody

Subcat	Description	Isotype	Conjugate	Price
ASPC1388	Anti-TNFRSF9 Antibody	Rat IgG2a, Kappa	None	$460	Add
ASPC1388-A	Anti-TNFRSF9 Antibody, APC	Rat IgG2a, Kappa	APC	$980	Add
ASPC1388-B	Anti-TNFRSF9 Antibody, Biotin	Rat IgG2a, Kappa	Biotin	$680	Add
ASPC1388-H	Anti-TNFRSF9 Antibody, HRP	Rat IgG2a, Kappa	HRP	$600	Add
ASPC1388-P	Anti-TNFRSF9 Antibody, PE	Rat IgG2a, Kappa	PE	$1,180	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC1388

Anti-TNFRSF9 Antibody

Rat IgG2a, Kappa

None

$460

Add

ASPC1388-A

Anti-TNFRSF9 Antibody, APC

Rat IgG2a, Kappa

APC

$980

Add

ASPC1388-B

Anti-TNFRSF9 Antibody, Biotin

Rat IgG2a, Kappa

Biotin

$680

Add

ASPC1388-H

Anti-TNFRSF9 Antibody, HRP

Rat IgG2a, Kappa

HRP

$600

Add

ASPC1388-P

Anti-TNFRSF9 Antibody, PE

Rat IgG2a, Kappa

$1,180

Add

Anti-TNFRSF9 Monoclonal Antibody
- Product Description:
  
  The Anti-TNFRSF9 antibody is a rat monoclonal antibody recommended for use in flow cytometry, activation and other applications. This antibody specifically targets TNFRSF9 and demonstrates reactivity with mouse.
  
  Applications:
  
  Flow Cytometry, Activation
  
  Source:
  
  Rat
  
  Target:
  
  TNFRSF9
  
  Specificity:
  
  This antibody reacts with TNFRSF9.
  
  Immunogen:
  
  Recombinant CD137.
  
  Clonality:
  
  Monoclonal
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-TNFRSF9 Monoclonal Antibody Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

Tnfrsf9

Protein Name

Tumor necrosis factor receptor superfamily member 9

Introduction

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.

Alternative Names

4-1BB; CD137; CDw137; ILA

Gene ID

21942

UniProt

P20334

Subcellular Location

Cell membrane

Tissue Specificity

Expressed in activated thymocytes, splenic T cells, CD4(+), and CD8(+) T-cells.

Function

Receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors (By similarity).

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