Anti-TNFRSF8 Monoclonal Antibody (Ki-4)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC028	Anti-TNFRSF8 Antibody (Ki-4)	Mouse IgG1, Kappa	None	$460	4-6 weeks	Add
ASPC028-P	Anti-TNFRSF8 Antibody (Ki-4), PE	Mouse IgG1, Kappa	PE	$1,180	2-3 weeks	Add
ASPC028-A	Anti-TNFRSF8 Antibody (Ki-4), APC	Mouse IgG1, Kappa	APC	$980	2-3 weeks	Add
ASPC028-H	Anti-TNFRSF8 Antibody (Ki-4), HRP	Mouse IgG1, Kappa	HRP	$600	2-3 weeks	Add
ASPC028-B	Anti-TNFRSF8 Antibody (Ki-4), Biotin	Mouse IgG1, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC028

Anti-TNFRSF8 Antibody (Ki-4)

Mouse IgG1, Kappa

None

$460

4-6 weeks

Add

ASPC028-P

Anti-TNFRSF8 Antibody (Ki-4), PE

Mouse IgG1, Kappa

$1,180

2-3 weeks

Add

ASPC028-A

Anti-TNFRSF8 Antibody (Ki-4), APC

Mouse IgG1, Kappa

APC

$980

2-3 weeks

Add

ASPC028-H

Anti-TNFRSF8 Antibody (Ki-4), HRP

Mouse IgG1, Kappa

HRP

$600

2-3 weeks

Add

ASPC028-B

Anti-TNFRSF8 Antibody (Ki-4), Biotin

Mouse IgG1, Kappa

Biotin

$680

2-3 weeks

Add

Anti-TNFRSF8 Monoclonal Antibody (Ki-4)
- Product Description:
  
  The Ki-4 antibody binds specifically to human CD30, a receptor expressed on the surface of certain cells, particularly activated T cells and B cells.
  
  Applications:
  
  Inhibition, Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Immunofluorescence, Immunohistochemistry
  
  Source:
  
  Mouse
  
  Target:
  
  TNFRSF8
  
  Target Species:
  
  Human
  
  Specificity:
  
  Human CD30
  
  Immunogen:
  
  Human TNFRSF8 protein
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  Ki-4
  
  Isotype:
  
  Mouse IgG1, Kappa
  
  Purification:
  
  The antibody was purified by Protein A.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for customized product form or formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-TNFRSF8 Monoclonal Antibody (Ki-4) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

TNFRSF8

Protein Name

Tumor necrosis factor receptor superfamily member 8

Molecular Family

CD Molecules

Introduction

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Alternative Names

TNF Receptor Superfamily Member 8; Lymphocyte Activation Antigen CD30; CD30L Receptor; Ki-1 Antigen; D1S166E; CD30

Gene ID

943

UniProt

P28908

Subcellular Location

Plasma membrane

Tissue Specificity

[Isoform 2]: Detected in alveolar macrophages (at protein level).

Cell Type

B cells, Dendritic cells, NK cells, Plasma cells, T cells

Function

Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B.

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