Anti-TNFRSF4 Monoclonal Antibody (1F2)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC510	Anti-TNFRSF4 Antibody (1F2)	Human IgG1	None	$460	In stock	Add
ASPC510-P	Anti-TNFRSF4 Antibody (1F2), PE	Human IgG1	PE	$1,180	2-3 weeks	Add
ASPC510-A	Anti-TNFRSF4 Antibody (1F2), APC	Human IgG1	APC	$980	2-3 weeks	Add
ASPC510-H	Anti-TNFRSF4 Antibody (1F2), HRP	Human IgG1	HRP	$600	2-3 weeks	Add
ASPC510-B	Anti-TNFRSF4 Antibody (1F2), Biotin	Human IgG1	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC510

Anti-TNFRSF4 Antibody (1F2)

Human IgG1

None

$460

In stock

Add

ASPC510-P

Anti-TNFRSF4 Antibody (1F2), PE

Human IgG1

$1,180

2-3 weeks

Add

ASPC510-A

Anti-TNFRSF4 Antibody (1F2), APC

Human IgG1

APC

$980

2-3 weeks

Add

ASPC510-H

Anti-TNFRSF4 Antibody (1F2), HRP

Human IgG1

HRP

$600

2-3 weeks

Add

ASPC510-B

Anti-TNFRSF4 Antibody (1F2), Biotin

Human IgG1

Biotin

$680

2-3 weeks

Add

Anti-TNFRSF4 Monoclonal Antibody (1F2)
- Product Description:
  
  The Anti-TNFRSF4 antibody is a human monoclonal antibody recommended for use in ELISA, western blot, functional assay and other applications. This antibody specifically targets TNFRSF4 and demonstrates reactivity with human and cynomolgus monkey.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Western Blot, Functional Assay
  
  Target:
  
  TNFRSF4
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human TNFRSF4.
  
  Immunogen:
  
  Human TNFRSF4 protein
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  1F2
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-TNFRSF4 Monoclonal Antibody (1F2) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

TNFRSF4

Protein Name

Tumor necrosis factor receptor superfamily member 4

Introduction

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.

Alternative Names

OX40; ACT35; CD134; IMD16; TXGP1L

Gene ID

7293

UniProt

P43489

Molecule Mass

CD Molecules, Immune Checkpoint Receptors

Related Disease

Immunodeficiency 16 (IMD16)

Subcellular Location

Membrane; Single-pass type I membrane protein.

Cell Line Specificity

Group enriched

Function

Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity.

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