Anti-TNFRSF17 Monoclonal Antibody (14B9)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC297	Anti-TNFRSF17 Antibody (14B9)	Human IgG1, Kappa	None	$460	In stock	Add
ASPC297-P	Anti-TNFRSF17 Antibody (14B9), PE	Human IgG1, Kappa	PE	$1,180	2-3 weeks	Add
ASPC297-A	Anti-TNFRSF17 Antibody (14B9), APC	Human IgG1, Kappa	APC	$980	2-3 weeks	Add
ASPC297-H	Anti-TNFRSF17 Antibody (14B9), HRP	Human IgG1, Kappa	HRP	$600	2-3 weeks	Add
ASPC297-B	Anti-TNFRSF17 Antibody (14B9), Biotin	Human IgG1, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC297

Anti-TNFRSF17 Antibody (14B9)

Human IgG1, Kappa

None

$460

In stock

Add

ASPC297-P

Anti-TNFRSF17 Antibody (14B9), PE

Human IgG1, Kappa

$1,180

2-3 weeks

Add

ASPC297-A

Anti-TNFRSF17 Antibody (14B9), APC

Human IgG1, Kappa

APC

$980

2-3 weeks

Add

ASPC297-H

Anti-TNFRSF17 Antibody (14B9), HRP

Human IgG1, Kappa

HRP

$600

2-3 weeks

Add

ASPC297-B

Anti-TNFRSF17 Antibody (14B9), Biotin

Human IgG1, Kappa

Biotin

$680

2-3 weeks

Add

Anti-TNFRSF17 Monoclonal Antibody (14B9)
- Product Description:
  
  The Anti-TNFRSF17 antibody is a human monoclonal antibody recommended for use in functional assay and other applications. This antibody specifically targets TNFRSF17 and demonstrates reactivity with human.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Functional Assay
  
  Target:
  
  TNFRSF17
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human BCMA.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  14B9
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-TNFRSF17 Monoclonal Antibody (14B9) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

TNFRSF17

Protein Name

Tumor necrosis factor receptor superfamily member 17

Introduction

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.

Alternative Names

BCM; BCMA; CD269; TNFRSF17; TNFRSF13A

Gene ID

608

UniProt

Q02223

Molecule Mass

CD Molecules

Subcellular Location

Cell membrane; Single-pass type III membrane protein. Endomembrane system; Single-pass type III membrane protein.

Tissue Specificity

Expressed in mature B-cells, but not in T-cells or monocytes.

Cell Line Specificity

Cancer enriched

Function

Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.

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