Anti-TNFRSF10B Monoclonal Antibody (3C7)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC212	Anti-TNFRSF10B Antibody (3C7)	Human IgG4, Kappa	None	$460	In stock	Add
ASPC212-P	Anti-TNFRSF10B Antibody (3C7), PE	Human IgG4, Kappa	PE	$1,180	2-3 weeks	Add
ASPC212-A	Anti-TNFRSF10B Antibody (3C7), APC	Human IgG4, Kappa	APC	$980	2-3 weeks	Add
ASPC212-H	Anti-TNFRSF10B Antibody (3C7), HRP	Human IgG4, Kappa	HRP	$600	2-3 weeks	Add
ASPC212-B	Anti-TNFRSF10B Antibody (3C7), Biotin	Human IgG4, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC212

Anti-TNFRSF10B Antibody (3C7)

Human IgG4, Kappa

None

$460

In stock

Add

ASPC212-P

Anti-TNFRSF10B Antibody (3C7), PE

Human IgG4, Kappa

$1,180

2-3 weeks

Add

ASPC212-A

Anti-TNFRSF10B Antibody (3C7), APC

Human IgG4, Kappa

APC

$980

2-3 weeks

Add

ASPC212-H

Anti-TNFRSF10B Antibody (3C7), HRP

Human IgG4, Kappa

HRP

$600

2-3 weeks

Add

ASPC212-B

Anti-TNFRSF10B Antibody (3C7), Biotin

Human IgG4, Kappa

Biotin

$680

2-3 weeks

Add

Anti-TNFRSF10B Monoclonal Antibody (3C7)
- Product Description:
  
  The Anti-TNFRSF10B antibody is a human monoclonal antibody recommended for use in ELISA, western blot, immunohistochemistry, functional assay and other applications. This antibody specifically targets TNFRSF10B and demonstrates reactivity with human.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Western Blot, Immunohistochemistry, Functional Assay
  
  Target:
  
  TNFRSF10B
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human DR5.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  3C7
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-TNFRSF10B Monoclonal Antibody (3C7) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

TNFRSF10B

Protein Name

Tumor necrosis factor receptor superfamily member 10B

Introduction

The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.

Alternative Names

DR5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5

Gene ID

8795

UniProt

O14763

Molecule Mass

CD Molecules, Cytokine/Chemokine Receptors

Related Disease

Squamous cell carcinoma of the head and neck (HNSCC)

Subcellular Location

Membrane; Single-pass type I membrane protein.

Cell Line Specificity

Low cancer specificity

Function

Receptor for the cytotoxic ligand TNFSF10/TRAIL.

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