Anti-TNC Monoclonal Antibody (3A11)

Anti-TNC Monoclonal Antibody (3A11)

Cat No: ASPC638

Summary
Host Species:
Human
Species Reactivity:
Human
Applications:
Enzyme-Linked Immunosorbent Assay, Surface Plasmon Resonance, Immunohistochemistry
Clone ID:
3A11
Clonality:
Monoclonal

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Product Information
Subcat Description Isotype Antibody Modification Conjugate Size Price Availability Quantity
ASPC638 Anti-TNC Antibody (3A11) Human IgG1, Lambda None $460 In stock
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ASPC638-P Anti-TNC Antibody (3A11), PE Human IgG1, Lambda PE $1,180 2-3 weeks
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ASPC638-A Anti-TNC Antibody (3A11), APC Human IgG1, Lambda APC $980 2-3 weeks
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ASPC638-H Anti-TNC Antibody (3A11), HRP Human IgG1, Lambda HRP $600 2-3 weeks
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ASPC638-B Anti-TNC Antibody (3A11), Biotin Human IgG1, Lambda Biotin $680 2-3 weeks
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Custom Antibody We can also offer conjugation antibodies (Alexa Fluor, Cy, APC, etc.) and other format antibodies (low endotoxin, Fab, scFv, etc.)

  • Anti-TNC Monoclonal Antibody (3A11)
    • Product Description:
      The Anti-TNC antibody is a human monoclonal antibody recommended for use in ELISA, surface plasmon resonance, immunohistochemistry and other applications. This antibody specifically targets TNC and demonstrates reactivity with human.
      Applications:
      Enzyme-Linked Immunosorbent Assay, Surface Plasmon Resonance, Immunohistochemistry
      Target:
      TNC
      Target Species:
      Human
      Specificity:
      This antibody reacts with human TNC.
      Clonality:
      Monoclonal
      Clone ID:
      3A11
      Purification:
      The antibody was purified by affinity chromatography.
      Purity:
      >95% as determined by SDS-PAGE
      Aggregation:
      <5% as determined by SEC
      Form:
      Liquid
      Endotoxin:
      Please contact us for more information.
      Formulation:
      Contact us for custom product formulation.
      Preservative:
      BSA and Azide free.
      Stabilizer:
      None
      Shipping:
      Shipped at 4°C.
      Storage:
      This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
  • Anti-TNC Monoclonal Antibody (3A11) Applications
    • Note:
      Optimal dilutions/concentrations should be determined by the end user.
Gene Symbol
TNC
Protein Name
Tenascin
Introduction
This gene encodes an extracellular matrix protein with a spatially and temporally restricted tissue distribution. This protein is homohexameric with disulfide-linked subunits, and contains multiple EGF-like and fibronectin type-III domains. It is implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity, and neuronal regeneration.
Alternative Names
GP; JI; TN; HXB; GMEM; TN-C; DFNA56; 150-225
Gene ID
UniProt
Related Disease
Deafness, autosomal dominant, 56 (DFNA56)
Subcellular Location
Secreted, extracellular space, extracellular matrix.
Tissue Specificity
Detected in fibroblasts (at protein level).
Cell Line Specificity
Cancer enhanced
Function
Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6. In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells.
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