Anti-THPO Monoclonal Antibody

Anti-THPO Monoclonal Antibody

Cat No: ASPC1377

Summary
Host Species:
Human
Species Reactivity:
Human
Applications:
Enzyme-Linked Immunosorbent Assay, Neutralization
Clonality:
Monoclonal

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Product Information
Subcat Description Isotype Antibody Modification Conjugate Size Price Quantity
ASPC1377 Anti-THPO Antibody Human IgG1, Kappa None $460
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ASPC1377-A Anti-THPO Antibody, APC Human IgG1, Kappa APC $980
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ASPC1377-B Anti-THPO Antibody, Biotin Human IgG1, Kappa Biotin $680
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ASPC1377-H Anti-THPO Antibody, HRP Human IgG1, Kappa HRP $600
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ASPC1377-P Anti-THPO Antibody, PE Human IgG1, Kappa PE $1,180
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Custom Antibody We can also offer conjugation antibodies (Alexa Fluor, Cy, APC, etc.) and other format antibodies (low endotoxin, Fab, scFv, etc.)

  • Anti-THPO Monoclonal Antibody
    • Product Description:
      The Anti-THPO antibody is a human monoclonal antibody recommended for use in enzyme-linked immunosorbent assay, neutralization and other applications. This antibody specifically targets THPO and demonstrates reactivity with human.
      Applications:
      Enzyme-Linked Immunosorbent Assay, Neutralization
      Target:
      THPO
      Target Species:
      Human
      Specificity:
      This antibody reacts with Human THPO.
      Immunogen:
      Recombinant human Thrombopoietin (TPO).
      Clonality:
      Monoclonal
      Purification:
      The antibody was purified by affinity chromatography.
      Purity:
      >95% as determined by SDS-PAGE
      Aggregation:
      <5% as determined by SEC
      Concentration:
      1 mg/mL
      Form:
      Liquid
      Endotoxin:
      Please contact us for more information.
      Formulation:
      Contact us for custom product formulation.
      Preservative:
      BSA and Azide free.
      Stabilizer:
      None
      Shipping:
      Shipped at 4°C.
      Storage:
      This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
  • Anti-THPO Monoclonal Antibody Applications
    • Note:
      Optimal dilutions/concentrations should be determined by the end user.
Gene Symbol
THPO
Protein Name
Thrombopoietin
Introduction
Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent.
Alternative Names
MGDF; MKCSF; ML; MPLLG; THCYT1; TPO
Gene ID
UniProt
Subcellular Location
Secreted
Cell Line Specificity
Cancer enhanced
Function
Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.
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