Anti-TGFA Monoclonal Antibody (tAb2)

Subcat	Description	Isotype	Conjugate	Price
ASPC1374	Anti-TGFA Antibody (tAb2)	Mouse IgG2a, Kappa	None	$460	Add
ASPC1374-A	Anti-TGFA Antibody (tAb2), APC	Mouse IgG2a, Kappa	APC	$980	Add
ASPC1374-B	Anti-TGFA Antibody (tAb2), Biotin	Mouse IgG2a, Kappa	Biotin	$680	Add
ASPC1374-H	Anti-TGFA Antibody (tAb2), HRP	Mouse IgG2a, Kappa	HRP	$600	Add
ASPC1374-P	Anti-TGFA Antibody (tAb2), PE	Mouse IgG2a, Kappa	PE	$1,180	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC1374

Anti-TGFA Antibody (tAb2)

Mouse IgG2a, Kappa

None

$460

Add

ASPC1374-A

Anti-TGFA Antibody (tAb2), APC

Mouse IgG2a, Kappa

APC

$980

Add

ASPC1374-B

Anti-TGFA Antibody (tAb2), Biotin

Mouse IgG2a, Kappa

Biotin

$680

Add

ASPC1374-H

Anti-TGFA Antibody (tAb2), HRP

Mouse IgG2a, Kappa

HRP

$600

Add

ASPC1374-P

Anti-TGFA Antibody (tAb2), PE

Mouse IgG2a, Kappa

$1,180

Add

Anti-TGFA Monoclonal Antibody (tAb2)
- Product Description:
  
  The Anti-TGFA antibody is a mouse monoclonal antibody recommended for use in enzyme-linked immunosorbent assay, dot blot and other applications. This antibody specifically targets TGFA and demonstrates reactivity with human.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Dot Blot
  
  Target:
  
  TGFA
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with Human TGFA.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  tAb2
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-TGFA Monoclonal Antibody (tAb2) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

TGFA

Protein Name

Protransforming growth factor alpha

Introduction

This gene encodes a growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative Names

TFGA

Gene ID

7039

UniProt

P01135

Subcellular Location

Transforming growth factor alpha: Secreted, extracellular space. Protransforming growth factor alpha: Cell membrane;

Tissue Specificity

Isoform 1, isoform 3 and isoform 4 are expressed in keratinocytes and tumor-derived cell lines.

Cell Line Specificity

Cancer enhanced

Function

TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.

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