Anti-TARDBP Monoclonal Antibody (11G7)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Price	Availability
ASPC496	Anti-TARDBP Antibody (11G7)	Mouse IgG2a, Kappa		None	$460	4-6 weeks	Add
ASPC496-1	Anti-TARDBP Antibody (11G7), Fab fragment	Mouse Fab	His tag	None	$460	In stock	Add
ASPC496-P	Anti-TARDBP Antibody (11G7), PE	Mouse IgG2a, Kappa		PE	$1,180	4-6 weeks	Add
ASPC496-A	Anti-TARDBP Antibody (11G7), APC	Mouse IgG2a, Kappa		APC	$980	4-6 weeks	Add
ASPC496-H	Anti-TARDBP Antibody (11G7), HRP	Mouse IgG2a, Kappa		HRP	$600	4-6 weeks	Add
ASPC496-B	Anti-TARDBP Antibody (11G7), Biotin	Mouse IgG2a, Kappa		Biotin	$680	4-6 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC496

Anti-TARDBP Antibody (11G7)

Mouse IgG2a, Kappa

None

$460

4-6 weeks

Add

ASPC496-1

Anti-TARDBP Antibody (11G7), Fab fragment

Mouse Fab

His tag

None

$460

In stock

Add

ASPC496-P

Anti-TARDBP Antibody (11G7), PE

Mouse IgG2a, Kappa

$1,180

4-6 weeks

Add

ASPC496-A

Anti-TARDBP Antibody (11G7), APC

Mouse IgG2a, Kappa

APC

$980

4-6 weeks

Add

ASPC496-H

Anti-TARDBP Antibody (11G7), HRP

Mouse IgG2a, Kappa

HRP

$600

4-6 weeks

Add

ASPC496-B

Anti-TARDBP Antibody (11G7), Biotin

Mouse IgG2a, Kappa

Biotin

$680

4-6 weeks

Add

Anti-TARDBP Monoclonal Antibody (11G7)
- Product Description:
  
  The Anti-TARDBP antibody is a mouse monoclonal antibody recommended for use in ELISA, flow cytometry, Radioimmunoassay and other applications. This antibody specifically targets TARDBP and demonstrates reactivity with human.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Radioimmunoassay, Western Blot
  
  Target:
  
  TARDBP
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human TARDBP.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  11G7
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-TARDBP Monoclonal Antibody (11G7) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

TARDBP

Protein Name

TAR DNA-binding protein 43

Introduction

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.

Alternative Names

TARDBP; TAR DNA binding protein; ALS10; TDP-43; TAR DNA-binding protein 43; TAR DNA-binding protein-43

Gene ID

23435

UniProt

Q13148

Related Disease

Amyotrophic lateral sclerosis 10 (ALS10)

Subcellular Location

Nucleus

Tissue Specificity

Ubiquitously expressed. In particular, expression is high in pancreas, placenta, lung, genital tract and spleen.

Cell Line Specificity

Low cancer specificity

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