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Anti-SQLE Monoclonal Antibody (C-11B3)
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Product Description:The Anti-SQLE antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human SQLE.Applications:Immunohistochemistry, Immunocytochemistry, Western Blot, ImmunoprecipitationSource:MouseTarget:SQLETarget Species:HumanSpecificity:This antibody reacts with human Squalene Epoxidase (SQLE).Clonality:MonoclonalClone ID:C-11B3Purification:The antibody was purified by affinity chromatography.Purity:>95% as determined by SDS-PAGEConcentration:1 mg/mLForm:LiquidFormulation:Contact us for custom product formulation.Preservative:0.02% sodium azideShipping:Shipped at 4°C.Storage:This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
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Anti-SQLE Monoclonal Antibody (C-11B3) Applications
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Recommended Dilution:Western Blot: 1:500-1:5000
Immunohistochemistry: 1:50-1:200
Immunocytochemistry: 1:50-1:200Note:Optimal dilutions/concentrations should be determined by the end user.
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Protein Name
Squalene monooxygenase
Introduction
Squalene epoxidase catalyzes the first oxygenation step in sterol biosynthesis and is thought to be one of the rate-limiting enzymes in this pathway.
Alternative Names
Squalene Epoxidase; Squalene Monooxygenase; SE; EC 1.14.14.17; ERG1
Gene ID
UniProt
Subcellular Location
Microsome membrane
Tissue Specificity
Detected in liver (at protein level).
Cell Line Specificity
Low cancer specificity
Function
Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
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