Anti-SOST Monoclonal Antibody (11H7)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC544	Anti-SOST Antibody (11H7)	Mouse IgG1, Kappa	None	$460	In stock	Add
ASPC544-P	Anti-SOST Antibody (11H7), PE	Mouse IgG1, Kappa	PE	$1,180	2-3 weeks	Add
ASPC544-A	Anti-SOST Antibody (11H7), APC	Mouse IgG1, Kappa	APC	$980	2-3 weeks	Add
ASPC544-H	Anti-SOST Antibody (11H7), HRP	Mouse IgG1, Kappa	HRP	$600	2-3 weeks	Add
ASPC544-B	Anti-SOST Antibody (11H7), Biotin	Mouse IgG1, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC544

Anti-SOST Antibody (11H7)

Mouse IgG1, Kappa

None

$460

In stock

Add

ASPC544-P

Anti-SOST Antibody (11H7), PE

Mouse IgG1, Kappa

$1,180

2-3 weeks

Add

ASPC544-A

Anti-SOST Antibody (11H7), APC

Mouse IgG1, Kappa

APC

$980

2-3 weeks

Add

ASPC544-H

Anti-SOST Antibody (11H7), HRP

Mouse IgG1, Kappa

HRP

$600

2-3 weeks

Add

ASPC544-B

Anti-SOST Antibody (11H7), Biotin

Mouse IgG1, Kappa

Biotin

$680

2-3 weeks

Add

Anti-SOST Monoclonal Antibody (11H7)
- Product Description:
  
  The Anti-SOST antibody is a mouse monoclonal antibody recommended for use in ELISA and other applications. This antibody specifically targets SOST and demonstrates reactivity with human, mouse.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay
  
  Target:
  
  SOST
  
  Specificity:
  
  This antibody reacts with human SOST.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  11H7
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-SOST Monoclonal Antibody (11H7) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

SOST

Protein Name

Sclerostin

Introduction

Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.

Alternative Names

SOST; sclerostin; CDD; VBCH; DAND6; SOST1

Gene ID

50964

UniProt

Q9BQB4

Related Disease

Sclerosteosis 1 (SOST1)

Subcellular Location

Secreted, extracellular space, extracellular matrix

Cell Line Specificity

Cancer enhanced

Function

Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.

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