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Anti-SLC52A2 Monoclonal Antibody (G-3A8)
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Product Description:The Anti-SLC52A2 antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human SLC52A2.Applications:Immunohistochemistry, Immunocytochemistry, Western Blot, ImmunoprecipitationSource:MouseTarget:SLC52A2Target Species:HumanSpecificity:This antibody reacts with human Solute Carrier Family 52 Member 2 (SLC52A2).Clonality:MonoclonalClone ID:G-3A8Purification:The antibody was purified by affinity chromatography.Purity:>95% as determined by SDS-PAGEConcentration:1 mg/mLForm:LiquidFormulation:Contact us for custom product formulation.Preservative:0.02% sodium azideShipping:Shipped at 4°C.Storage:This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
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Anti-SLC52A2 Monoclonal Antibody (G-3A8) Applications
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Recommended Dilution:Western Blot: 1:500-1:5000
Immunohistochemistry: 1:50-1:200
Immunocytochemistry: 1:50-1:200Note:Optimal dilutions/concentrations should be determined by the end user.
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Protein Name
Solute carrier family 52, riboflavin transporter, member 2
Introduction
This gene encodes a membrane protein which belongs to the riboflavin transporter family. In humans, riboflavin must be obtained by intestinal absorption because it cannot be synthesized by the body. The water-soluble vitamin riboflavin is processed to the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) which then act as intermediaries in many cellular metabolic reactions. Paralogous members of the riboflavin transporter gene family are located on chromosomes 17 and 20. Unlike other members of this family, this gene has higher expression in brain tissue than small intestine. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene have been associated with Brown-Vialetto-Van Laere syndrome 2 - an autosomal recessive progressive neurologic disorder characterized by deafness, bulbar dysfunction, and axial and limb hypotonia.
Alternative Names
BVVLS2; D15Ertd747e; GPCR41; GPR172A; PAR1; RFT3; RFVT2; hRFT3
Gene ID
UniProt
Related Disease
Brown-Vialetto-Van Laere syndrome 2 (BVVLS2)
Subcellular Location
Cell membrane
Tissue Specificity
Highly expressed in brain, fetal brain and salivary gland. Weakly expressed in other tissues.
Cell Line Specificity
Low cancer specificity
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