Anti-SIGLEC10 Monoclonal Antibody (14F7)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC647	Anti-SIGLEC10 Antibody (14F7)	Mouse IgG2a, Kappa	None	$460	In stock	Add
ASPC647-P	Anti-SIGLEC10 Antibody (14F7), PE	Mouse IgG2a, Kappa	PE	$1,180	2-3 weeks	Add
ASPC647-A	Anti-SIGLEC10 Antibody (14F7), APC	Mouse IgG2a, Kappa	APC	$980	2-3 weeks	Add
ASPC647-H	Anti-SIGLEC10 Antibody (14F7), HRP	Mouse IgG2a, Kappa	HRP	$600	2-3 weeks	Add
ASPC647-B	Anti-SIGLEC10 Antibody (14F7), Biotin	Mouse IgG2a, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC647

Anti-SIGLEC10 Antibody (14F7)

Mouse IgG2a, Kappa

None

$460

In stock

Add

ASPC647-P

Anti-SIGLEC10 Antibody (14F7), PE

Mouse IgG2a, Kappa

$1,180

2-3 weeks

Add

ASPC647-A

Anti-SIGLEC10 Antibody (14F7), APC

Mouse IgG2a, Kappa

APC

$980

2-3 weeks

Add

ASPC647-H

Anti-SIGLEC10 Antibody (14F7), HRP

Mouse IgG2a, Kappa

HRP

$600

2-3 weeks

Add

ASPC647-B

Anti-SIGLEC10 Antibody (14F7), Biotin

Mouse IgG2a, Kappa

Biotin

$680

2-3 weeks

Add

Anti-SIGLEC10 Monoclonal Antibody (14F7)
- Product Description:
  
  The Anti-SIGLEC10 antibody is a mouse monoclonal antibody recommended for use in ELISA and other applications. This antibody specifically targets SIGLEC10 and demonstrates reactivity with human.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Western Blot
  
  Target:
  
  SIGLEC10
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human SIGLEC10.
  
  Immunogen:
  
  The extracellular domain of Human SIGLEC10
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  14F7
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-SIGLEC10 Monoclonal Antibody (14F7) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

SIGLEC10

Protein Name

Sialic acid-binding Ig-like lectin 10

Introduction

Diseases associated with SIGLEC10 include Stargardt Disease. Among its related pathways are Class I MHC mediated antigen processing and presentation and Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell.

Alternative Names

Sialic Acid Binding Ig Like Lectin 10; Siglec-Like Protein 2; SLG2; Sialic Acid Binding Ig-Like Lectin 10; PRO940

Gene ID

89790

UniProt

Q96LC7

Cell Line Specificity

Group enriched

Function

Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid (By similarity). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, seems to act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.

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