-
Anti-SH3BP2 Monoclonal Antibody (D-9A7)
-
Product Description:The Anti-SH3BP2 antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human SH3BP2.Applications:Immunohistochemistry, Immunocytochemistry, Western Blot, ImmunoprecipitationSource:MouseTarget:SH3BP2Target Species:HumanSpecificity:This antibody reacts with human SH3 Domain Binding Protein 2 (SH3BP2).Clonality:MonoclonalClone ID:D-9A7Purification:The antibody was purified by affinity chromatography.Purity:>95% as determined by SDS-PAGEConcentration:1 mg/mLForm:LiquidFormulation:Contact us for custom product formulation.Preservative:0.02% sodium azideShipping:Shipped at 4°C.Storage:This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
-
-
Anti-SH3BP2 Monoclonal Antibody (D-9A7) Applications
-
Recommended Dilution:Western Blot: 1:500-1:5000
Immunohistochemistry: 1:50-1:200
Immunocytochemistry: 1:50-1:200Note:Optimal dilutions/concentrations should be determined by the end user.
-
Protein Name
SH3 domain-binding protein 2
Introduction
The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases, and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.
Alternative Names
3BP-2; 3BP2; CRBM; CRPM; RES4-23
Gene ID
UniProt
Related Disease
Cherubism (CRBM)
Tissue Specificity
Expressed in a variety of tissues including lung, liver, skeletal muscle, kidney and pancreas.
Cell Line Specificity
Low cancer specificity
Function
Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. Binds to phosphatidylinositols; linking the hemopoietic tyrosine kinase fes to the cytoplasmic membrane in a phosphorylation dependent mechanism.
Customer Reviews
There are no reviews for Product Name.
Submit a review and receive an Amazon gift card.
Publications
There are no publications for Product Name.
If you couldn't find the specific publication, you can:
Submit a Citation Get a Publication Reward
