-
Anti-SERPIND1 Monoclonal Antibody (G-2C5)
-
Product Description:The Anti-SERPIND1 antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human SERPIND1.Applications:Immunohistochemistry, Immunocytochemistry, Western Blot, ImmunoprecipitationSource:MouseTarget:SERPIND1Target Species:HumanSpecificity:This antibody reacts with human Serpin Family D Member 1 (SERPIND1).Clonality:MonoclonalClone ID:G-2C5Purification:The antibody was purified by affinity chromatography.Purity:>95% as determined by SDS-PAGEConcentration:1 mg/mLForm:LiquidFormulation:Contact us for custom product formulation.Preservative:0.02% sodium azideShipping:Shipped at 4°C.Storage:This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
-
-
Anti-SERPIND1 Monoclonal Antibody (G-2C5) Applications
-
Recommended Dilution:Western Blot: 1:500-1:5000
Immunohistochemistry: 1:50-1:200
Immunocytochemistry: 1:50-1:200Note:Optimal dilutions/concentrations should be determined by the end user.
-
Protein Name
Heparin cofactor 2
Introduction
This gene belongs to the serpin gene superfamily. Serpins play roles in many processes including inflammation, blood clotting, and cancer metastasis. Members of this family have highly conserved secondary structures with a reactive center loop that interacts with the protease active site to inhibit protease activity. This gene encodes a plasma serine protease that functions as a thrombin and chymotrypsin inhibitor. The protein is activated by heparin, dermatan sulfate, and glycosaminoglycans. Allelic variations in this gene are associated with heparin cofactor II deficiency.
Alternative Names
D22S673; HC2; HCF2; HCII; HLS2; LS2; THPH10
Gene ID
UniProt
Related Disease
Thrombophilia due to heparin cofactor 2 deficiency (THPH10)
Tissue Specificity
Expressed predominantly in liver. Also present in plasma.
Cell Line Specificity
Group enriched
Function
Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner.
Customer Reviews
There are no reviews for Product Name.
Submit a review and receive an Amazon gift card.
Publications
There are no publications for Product Name.
If you couldn't find the specific publication, you can:
Submit a Citation Get a Publication Reward
