Anti-SERPINA1 Monoclonal Antibody (3G6)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Price	Availability
ASPC715	Anti-SERPINA1 Antibody (3G6)	Mouse IgG1, Kappa		None	$460	4-6 weeks	Add
ASPC715-1	Anti-SERPINA1 Antibody (3G6), Fab fragment	Mouse Fab	His tag	None	$460	In stock	Add
ASPC715-P	Anti-SERPINA1 Antibody (3G6), PE	Mouse IgG1, Kappa		PE	$1,180	4-6 weeks	Add
ASPC715-A	Anti-SERPINA1 Antibody (3G6), APC	Mouse IgG1, Kappa		APC	$980	4-6 weeks	Add
ASPC715-H	Anti-SERPINA1 Antibody (3G6), HRP	Mouse IgG1, Kappa		HRP	$600	4-6 weeks	Add
ASPC715-B	Anti-SERPINA1 Antibody (3G6), Biotin	Mouse IgG1, Kappa		Biotin	$680	4-6 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC715

Anti-SERPINA1 Antibody (3G6)

Mouse IgG1, Kappa

None

$460

4-6 weeks

Add

ASPC715-1

Anti-SERPINA1 Antibody (3G6), Fab fragment

Mouse Fab

His tag

None

$460

In stock

Add

ASPC715-P

Anti-SERPINA1 Antibody (3G6), PE

Mouse IgG1, Kappa

$1,180

4-6 weeks

Add

ASPC715-A

Anti-SERPINA1 Antibody (3G6), APC

Mouse IgG1, Kappa

APC

$980

4-6 weeks

Add

ASPC715-H

Anti-SERPINA1 Antibody (3G6), HRP

Mouse IgG1, Kappa

HRP

$600

4-6 weeks

Add

ASPC715-B

Anti-SERPINA1 Antibody (3G6), Biotin

Mouse IgG1, Kappa

Biotin

$680

4-6 weeks

Add

Anti-SERPINA1 Monoclonal Antibody (3G6)
- Product Description:
  
  The Anti-SERPINA1 antibody is a mouse monoclonal antibody recommended for use in ELISA, inhibition and other applications. This antibody specifically targets SERPINA1 and demonstrates reactivity with human.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Inhibition
  
  Target:
  
  SERPINA1
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human SERPINA1.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  3G6
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-SERPINA1 Monoclonal Antibody (3G6) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

SERPINA1

Protein Name

Alpha-1-antitrypsin

Introduction

The protein encoded by this gene is a serine protease inhibitor belonging to the serpin superfamily whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. This protein is produced in the liver, the bone marrow, by lymphocytic and monocytic cells in lymphoid tissue, and by the Paneth cells of the gut. Defects in this gene are associated with chronic obstructive pulmonary disease, emphysema, and chronic liver disease.

Alternative Names

PI; A1A; AAT; PI1; A1AT; nNIF; PRO2275; alpha1AT

Gene ID

5265

UniProt

P01009

Related Disease

Alpha-1-antitrypsin deficiency (A1ATD)

Tissue Specificity

Ubiquitous. Expressed in leukocytes and plasma.

Cell Line Specificity

Cancer enhanced

Function

Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.

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