Anti-SELE Monoclonal Antibody (7A9)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC102	Anti-SELE Antibody (7A9)	Mouse IgG1, Kappa	None	$460	In stock	Add
ASPC102-P	Anti-SELE Antibody (7A9), PE	Mouse IgG1, Kappa	PE	$1,180	2-3 weeks	Add
ASPC102-A	Anti-SELE Antibody (7A9), APC	Mouse IgG1, Kappa	APC	$980	2-3 weeks	Add
ASPC102-H	Anti-SELE Antibody (7A9), HRP	Mouse IgG1, Kappa	HRP	$600	2-3 weeks	Add
ASPC102-B	Anti-SELE Antibody (7A9), Biotin	Mouse IgG1, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC102

Anti-SELE Antibody (7A9)

Mouse IgG1, Kappa

None

$460

In stock

Add

ASPC102-P

Anti-SELE Antibody (7A9), PE

Mouse IgG1, Kappa

$1,180

2-3 weeks

Add

ASPC102-A

Anti-SELE Antibody (7A9), APC

Mouse IgG1, Kappa

APC

$980

2-3 weeks

Add

ASPC102-H

Anti-SELE Antibody (7A9), HRP

Mouse IgG1, Kappa

HRP

$600

2-3 weeks

Add

ASPC102-B

Anti-SELE Antibody (7A9), Biotin

Mouse IgG1, Kappa

Biotin

$680

2-3 weeks

Add

Anti-SELE Monoclonal Antibody (7A9)
- Product Description:
  
  7A9 is a monoclonal antibody specifically developed to recognize and bind to endothelial leukocyte adhesion molecule-1 (ELAM-1), also known as E-selectin. ELAM-1 is a cell adhesion molecule expressed on endothelial cells and plays a crucial role in the inflammatory response by mediating the adhesion of leukocytes (white blood cells) to the endothelium.
  
  Applications:
  
  Blocking, Enzyme-Linked Immunosorbent Assay
  
  Source:
  
  Mouse
  
  Target:
  
  SELE
  
  Target Species:
  
  Human
  
  Specificity:
  
  Human ELAM1
  
  Immunogen:
  
  Human endothelial cells activated with IL-1
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  7A9
  
  Isotype:
  
  Mouse IgG1, Kappa
  
  Purification:
  
  The antibody was purified by Protein A.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for customized product form or formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-SELE Monoclonal Antibody (7A9) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

SELE

Protein Name

E-selectin

Molecular Family

Adhesion Molecules, CD Molecules

Introduction

The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.

Alternative Names

Selectin E; Endothelial Leukocyte Adhesion Molecule 1; CD62 Antigen-Like Family Member E; Endothelial Adhesion Molecule 1; ELAM-1; LECAM2; ELAM1; Leukocyte Endothelial Cell Adhesion Molecule 2

Gene ID

6401

UniProt

P16581

Cell Type

Endothelial cells

Function

Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis.

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