Anti-RYR1 Monoclonal Antibody (C-2G9)

Anti-RYR1 Monoclonal Antibody (C-2G9)

Cat No: ASZ1C1584

Summary
Host Species:
Mouse
Species Reactivity:
Human
Applications:
Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
Clone ID:
C-2G9
Clonality:
Monoclonal

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Product Information
Subcat Description Isotype Antibody Modification Conjugate Size Price Quantity
ASZ1C1584 Anti-RYR1 Antibody (C-2G9) Mouse IgG None $460
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  • Anti-RYR1 Monoclonal Antibody (C-2G9)
    • Product Description:
      The Anti-RYR1 antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human RYR1.
      Applications:
      Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
      Source:
      Mouse
      Target:
      RYR1
      Target Species:
      Human
      Specificity:
      This antibody reacts with human Ryanodine Receptor 1 (RYR1).
      Clonality:
      Monoclonal
      Clone ID:
      C-2G9
      Purification:
      The antibody was purified by affinity chromatography.
      Purity:
      >95% as determined by SDS-PAGE
      Concentration:
      1 mg/mL
      Form:
      Liquid
      Formulation:
      Contact us for custom product formulation.
      Preservative:
      0.02% sodium azide
      Shipping:
      Shipped at 4°C.
      Storage:
      This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
  • Anti-RYR1 Monoclonal Antibody (C-2G9) Applications
    • Recommended Dilution:
      Western Blot: 1:500-1:5000
      Immunohistochemistry: 1:50-1:200
      Immunocytochemistry: 1:50-1:200
      Note:
      Optimal dilutions/concentrations should be determined by the end user.
Protein Name
Ryanodine receptor 1
Introduction
This gene encodes a ryanodine receptor found in skeletal muscle. The encoded protein functions as a calcium release channel in the sarcoplasmic reticulum but also serves to connect the sarcoplasmic reticulum and transverse tubule. Mutations in this gene are associated with malignant hyperthermia susceptibility, central core disease, and minicore myopathy with external ophthalmoplegia. Alternatively spliced transcripts encoding different isoforms have been described.
Alternative Names
CCO; MHS; MHS1; PPP1R137; RYDR; RYR; RYR-1; SKRR
Gene ID
UniProt
Related Disease
Malignant hyperthermia 1 (MHS1)
Subcellular Location
Sarcoplasmic reticulum membrane
Tissue Specificity
Skeletal muscle and brain (cerebellum and hippocampus).
Cell Line Specificity
Cancer enhanced
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