Anti-Rotavirus A VP7 Monoclonal Antibody (4F8)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC248	Anti-Rotavirus A VP7 Antibody (4F8)	Mouse IgG1, Kappa	None	$460	In stock	Add
ASPC248-P	Anti-Rotavirus A VP7 Antibody (4F8), PE	Mouse IgG1, Kappa	PE	$1,180	2-3 weeks	Add
ASPC248-A	Anti-Rotavirus A VP7 Antibody (4F8), APC	Mouse IgG1, Kappa	APC	$980	2-3 weeks	Add
ASPC248-H	Anti-Rotavirus A VP7 Antibody (4F8), HRP	Mouse IgG1, Kappa	HRP	$600	2-3 weeks	Add
ASPC248-B	Anti-Rotavirus A VP7 Antibody (4F8), Biotin	Mouse IgG1, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC248

Anti-Rotavirus A VP7 Antibody (4F8)

Mouse IgG1, Kappa

None

$460

In stock

Add

ASPC248-P

Anti-Rotavirus A VP7 Antibody (4F8), PE

Mouse IgG1, Kappa

$1,180

2-3 weeks

Add

ASPC248-A

Anti-Rotavirus A VP7 Antibody (4F8), APC

Mouse IgG1, Kappa

APC

$980

2-3 weeks

Add

ASPC248-H

Anti-Rotavirus A VP7 Antibody (4F8), HRP

Mouse IgG1, Kappa

HRP

$600

2-3 weeks

Add

ASPC248-B

Anti-Rotavirus A VP7 Antibody (4F8), Biotin

Mouse IgG1, Kappa

Biotin

$680

2-3 weeks

Add

Anti-Rotavirus A VP7 Monoclonal Antibody (4F8)
- Product Description:
  
  The Anti-Rotavirus A VP7 antibody is a mouse monoclonal antibody recommended for use in neutralization and other applications. This antibody specifically targets Rotavirus A VP7.
  
  Applications:
  
  Neutralization, Enzyme-Linked Immunosorbent Assay
  
  Target:
  
  Rotavirus A VP7
  
  Target Species:
  
  Rotavirus A
  
  Specificity:
  
  This antibody reacts with Rotavirus A VP7.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  4F8
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-Rotavirus A VP7 Monoclonal Antibody (4F8) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Introduction

Rotavirus is a genus of double-stranded RNA viruses in the family Reoviridae. There are nine species of the genus, referred to as A, B, C, D, F, G, H, I and J. Rotavirus A is the most common species, and these rotaviruses cause more than 90% of rotavirus infections in humans.

Alternative Names

VP7; RAV VP7; RV-A

Gene ID

7011359

UniProt

A2T3P5

Subcellular Location

Virion

Function

Calcium-binding protein that interacts with rotavirus cell receptors once the initial attachment by VP4 has been achieved. Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors. Following entry into the host cell, low intracellular or intravesicular Ca(2+) concentration probably causes the calcium-stabilized VP7 trimers to dissociate from the virion. This step is probably necessary for the membrane-disrupting entry step and the release of VP4, which is locked onto the virion by VP7 (By similarity).

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