Anti-ROBO1 Monoclonal Antibody (B2212A)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC016	Anti-ROBO1 Antibody (B2212A)	Mouse IgG, Kappa	None	$460	In stock	Add
ASPC016-P	Anti-ROBO1 Antibody (B2212A), PE	Mouse IgG, Kappa	PE	$1,180	2-3 weeks	Add
ASPC016-A	Anti-ROBO1 Antibody (B2212A), APC	Mouse IgG, Kappa	APC	$980	2-3 weeks	Add
ASPC016-H	Anti-ROBO1 Antibody (B2212A), HRP	Mouse IgG, Kappa	HRP	$600	2-3 weeks	Add
ASPC016-B	Anti-ROBO1 Antibody (B2212A), Biotin	Mouse IgG, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC016

Anti-ROBO1 Antibody (B2212A)

Mouse IgG, Kappa

None

$460

In stock

Add

ASPC016-P

Anti-ROBO1 Antibody (B2212A), PE

Mouse IgG, Kappa

$1,180

2-3 weeks

Add

ASPC016-A

Anti-ROBO1 Antibody (B2212A), APC

Mouse IgG, Kappa

APC

$980

2-3 weeks

Add

ASPC016-H

Anti-ROBO1 Antibody (B2212A), HRP

Mouse IgG, Kappa

HRP

$600

2-3 weeks

Add

ASPC016-B

Anti-ROBO1 Antibody (B2212A), Biotin

Mouse IgG, Kappa

Biotin

$680

2-3 weeks

Add

Anti-ROBO1 Monoclonal Antibody (B2212A)
- Product Description:
  
  The antibody B2212A specifically recognizes the fn3 domain within the extracellular region of the ROBO-1 protein. The fn3 domain is a structural motif found in a variety of proteins involved in cell adhesion and receptor-ligand interactions.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Western Blot
  
  Source:
  
  Mouse
  
  Target:
  
  ROBO1
  
  Target Species:
  
  Human
  
  Specificity:
  
  Human ROBO1
  
  Immunogen:
  
  Recombinant human ROBO1 protein
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  B2212A
  
  Isotype:
  
  Mouse IgG, Kappa
  
  Purification:
  
  The antibody was purified by Protein A.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for customized product form or formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-ROBO1 Monoclonal Antibody (B2212A) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

ROBO1

Protein Name

Roundabout homolog 1

Introduction

Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative Names

Roundabout Guidance Receptor 1; Deleted In U Twenty Twenty; DUTT1; Roundabout, Axon Guidance Receptor, Homolog 1 (Drosophila); Roundabout (Axon Guidance Receptor, Drosophila) Homolog 1; Roundabout, Axon Guidance Receptor, Homolog 1; Roundabout Homolog 1; H-Robo-1; SAX3

Gene ID

6091

UniProt

Q9Y6N7

Related Disease

Neurooculorenal syndrome (NORS)

Subcellular Location

Plasma membrane

Tissue Specificity

Widely expressed, with exception of kidney.

Cell Type

B cells, Lymphocytes