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Anti-RAD23B Monoclonal Antibody (SAIC-28B-8)
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Product Description:The Anti-RAD23B antibody is a mouse monoclonal antibody recommended for use in enzyme-linked immunosorbent assay, western blot and other applications. This antibody specifically targets RAD23B and demonstrates reactivity with human.Applications:Enzyme-Linked Immunosorbent Assay, Western blotTarget:RAD23BTarget Species:HumanSpecificity:This antibody reacts with Human RAD23B.Immunogen:Peptide conjugated to KLH.Clonality:MonoclonalClone ID:SAIC-28B-8Purification:The antibody was purified by affinity chromatography.Purity:>95% as determined by SDS-PAGEAggregation:<5% as determined by SECConcentration:1 mg/mLForm:LiquidEndotoxin:Please contact us for more information.Formulation:Contact us for custom product formulation.Preservative:BSA and Azide free.Stabilizer:NoneShipping:Shipped at 4°C.Storage:This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
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Anti-RAD23B Monoclonal Antibody (SAIC-28B-8) Applications
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Note:Optimal dilutions/concentrations should be determined by the end user.
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Gene Symbol
RAD23B
Protein Name
UV excision repair protein RAD23 homolog B
Introduction
The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Alternative Names
HHR23B; HR23B; P58
Gene ID
UniProt
Subcellular Location
Nucleus. Cytoplasm.
Cell Line Specificity
Low cancer specificity
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