Anti-QDPR Monoclonal Antibody (B-10D8)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Size	Price	Quantity
ASZ1C1513	Anti-QDPR Antibody (B-10D8)	Mouse IgG		None		$460		Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASZ1C1513

Anti-QDPR Antibody (B-10D8)

Mouse IgG

None

$460

Add

Anti-QDPR Monoclonal Antibody (B-10D8)
- Product Description:
  
  The Anti-QDPR antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human QDPR.
  
  Applications:
  
  Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
  
  Source:
  
  Mouse
  
  Target:
  
  QDPR
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human Quinoid Dihydropteridine Reductase (QDPR).
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  B-10D8
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  0.02% sodium azide
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-QDPR Monoclonal Antibody (B-10D8) Applications
- Recommended Dilution:
  
  Western Blot: 1:500-1:5000
  Immunohistochemistry: 1:50-1:200
  Immunocytochemistry: 1:50-1:200
  
  Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Protein Name

Dihydropteridine reductase

Introduction

This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.

Alternative Names

DHPR; PKU2; SDR33C1

Gene ID

5860

UniProt

P09417

Related Disease

Hyperphenylalaninemia, BH4-deficient, C (HPABH4C)

Cell Line Specificity

Low cancer specificity

Function

Catalyzes the conversion of quinonoid dihydrobiopterin into tetrahydrobiopterin.