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Anti-PTPRS Monoclonal Antibody (13H1)
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Product Description:The Anti-PTPRS antibody is a mouse monoclonal antibody recommended for use in ELISA, immunoprecipitation, functional assay and other applications. This antibody specifically targets PTPRS and demonstrates reactivity with human.Applications:Enzyme-Linked Immunosorbent Assay, Immunoprecipitation, Functional AssayTarget:PTPRSTarget Species:HumanSpecificity:This antibody reacts with human PTPRS.Immunogen:Human PTPRS proteinClonality:MonoclonalClone ID:13H1Purification:The antibody was purified by affinity chromatography.Purity:>95% as determined by SDS-PAGEAggregation:<5% as determined by SECForm:LiquidEndotoxin:Please contact us for more information.Formulation:Contact us for custom product formulation.Preservative:BSA and Azide free.Stabilizer:NoneShipping:Shipped at 4°C.Storage:This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
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Anti-PTPRS Monoclonal Antibody (13H1) Applications
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Note:Optimal dilutions/concentrations should be determined by the end user.
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Gene Symbol
PTPRS
Protein Name
Receptor-type tyrosine-protein phosphatase S
Introduction
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.
Alternative Names
PTPRS; protein tyrosine phosphatase, receptor type, S; PTPSIGMA; receptor-type tyrosine-protein phosphatase S; R-PTP-S; R-PTP-sigma; protein tyrosine phosphatase PTPsigma; receptor-type tyrosine-protein phosphatase sigma
Gene ID
UniProt
Subcellular Location
Cell membrane
Cell Line Specificity
Low cancer specificity
Function
Cell surface receptor that binds to glycosaminoglycans, including chondroitin sulfate proteoglycans and heparan sulfate proteoglycan.
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