Anti-PTGDR2 Monoclonal Antibody (2C3)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC337	Anti-PTGDR2 Antibody (2C3)	Mouse IgG2a, Kappa	None	$460	In stock	Add
ASPC337-P	Anti-PTGDR2 Antibody (2C3), PE	Mouse IgG2a, Kappa	PE	$1,180	2-3 weeks	Add
ASPC337-A	Anti-PTGDR2 Antibody (2C3), APC	Mouse IgG2a, Kappa	APC	$980	2-3 weeks	Add
ASPC337-H	Anti-PTGDR2 Antibody (2C3), HRP	Mouse IgG2a, Kappa	HRP	$600	2-3 weeks	Add
ASPC337-B	Anti-PTGDR2 Antibody (2C3), Biotin	Mouse IgG2a, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC337

Anti-PTGDR2 Antibody (2C3)

Mouse IgG2a, Kappa

None

$460

In stock

Add

ASPC337-P

Anti-PTGDR2 Antibody (2C3), PE

Mouse IgG2a, Kappa

$1,180

2-3 weeks

Add

ASPC337-A

Anti-PTGDR2 Antibody (2C3), APC

Mouse IgG2a, Kappa

APC

$980

2-3 weeks

Add

ASPC337-H

Anti-PTGDR2 Antibody (2C3), HRP

Mouse IgG2a, Kappa

HRP

$600

2-3 weeks

Add

ASPC337-B

Anti-PTGDR2 Antibody (2C3), Biotin

Mouse IgG2a, Kappa

Biotin

$680

2-3 weeks

Add

Anti-PTGDR2 Monoclonal Antibody (2C3)
- Product Description:
  
  The Anti-PTGDR2 antibody is a mouse monoclonal antibody recommended for use in flow cytometry, immunofluorescence and other applications. This antibody specifically targets PTGDR2 and demonstrates reactivity with cynomolgus monkey.
  
  Applications:
  
  Flow Cytometry, Immunofluorescence
  
  Target:
  
  PTGDR2
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human PTGDR2.
  
  Immunogen:
  
  Human PTGDR2 protein
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  2C3
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-PTGDR2 Monoclonal Antibody (2C3) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

PTGDR2

Protein Name

Prostaglandin D2 receptor 2

Introduction

This gene encodes a cell-surface anchored serine protease, which is a member of the trypsin family of serine proteases. The encoded protein is predicted to be active on peptide linkages involving the carboxyl group of lysine or arginine. The encoded protein localizes to the cytoplasm and the plasma membrane of premeiotic testicular germ cells and may be involved in progression of testicular tumors of germ cell origin. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative Names

PTGDR2; prostaglandin D2 receptor 2; DP2; DL1R; CD294; CRTH2; GPR44

Gene ID

11251

UniProt

Q9Y5Y4

Molecule Mass

CD Molecules

Subcellular Location

Cell membrane

Cell Line Specificity

Cancer enriched

Function

Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses.

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