Anti-pT231-tau Monoclonal Antibody (10A1)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Price	Availability
ASPC729	Anti-pT231-tau Antibody (10A1)	Mouse IgG1, Kappa		None	$460	4-6 weeks	Add
ASPC729-1	Anti-pT231-tau Antibody (10A1), Fab fragment	Mouse Fab	His tag	None	$460	In stock	Add
ASPC729-P	Anti-pT231-tau Antibody (10A1), PE	Mouse IgG1, Kappa		PE	$1,180	4-6 weeks	Add
ASPC729-A	Anti-pT231-tau Antibody (10A1), APC	Mouse IgG1, Kappa		APC	$980	4-6 weeks	Add
ASPC729-H	Anti-pT231-tau Antibody (10A1), HRP	Mouse IgG1, Kappa		HRP	$600	4-6 weeks	Add
ASPC729-B	Anti-pT231-tau Antibody (10A1), Biotin	Mouse IgG1, Kappa		Biotin	$680	4-6 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC729

Anti-pT231-tau Antibody (10A1)

Mouse IgG1, Kappa

None

$460

4-6 weeks

Add

ASPC729-1

Anti-pT231-tau Antibody (10A1), Fab fragment

Mouse Fab

His tag

None

$460

In stock

Add

ASPC729-P

Anti-pT231-tau Antibody (10A1), PE

Mouse IgG1, Kappa

$1,180

4-6 weeks

Add

ASPC729-A

Anti-pT231-tau Antibody (10A1), APC

Mouse IgG1, Kappa

APC

$980

4-6 weeks

Add

ASPC729-H

Anti-pT231-tau Antibody (10A1), HRP

Mouse IgG1, Kappa

HRP

$600

4-6 weeks

Add

ASPC729-B

Anti-pT231-tau Antibody (10A1), Biotin

Mouse IgG1, Kappa

Biotin

$680

4-6 weeks

Add

Anti-pT231-tau Monoclonal Antibody (10A1)
- Product Description:
  
  The Anti-pT231-tau antibody is a mouse monoclonal antibody recommended for use in ELISA, immunohistochemistry, neutralization, functional assay and other applications. This antibody specifically targets pT231-tau and demonstrates reactivity with human.
  
  Applications:
  
  Enzyme-Linked Immunosorbent Assay, Immunohistochemistry, Neutralization, Functional Assay
  
  Target:
  
  pT231-tau
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human pT231-tau.
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  10A1
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-pT231-tau Monoclonal Antibody (10A1) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

MAPT

Protein Name

Microtubule-associated protein tau

Introduction

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Alternative Names

pT231-tau

Gene ID

4137

UniProt

P10636

Molecule Mass

Tau

Related Disease

Alzheimer disease

Subcellular Location

Cytoplasm, cytosol

Tissue Specificity

Expressed in neurons. Isoform PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.

Cell Line Specificity

Group enriched

Function

Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity.

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