Anti-PRNP Monoclonal Antibody (mAb 132)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC126	Anti-PRNP Antibody (mAb 132)	Mouse IgG1, Kappa	None	$460	In stock	Add
ASPC126-P	Anti-PRNP Antibody (mAb 132), PE	Mouse IgG1, Kappa	PE	$1,180	2-3 weeks	Add
ASPC126-A	Anti-PRNP Antibody (mAb 132), APC	Mouse IgG1, Kappa	APC	$980	2-3 weeks	Add
ASPC126-H	Anti-PRNP Antibody (mAb 132), HRP	Mouse IgG1, Kappa	HRP	$600	2-3 weeks	Add
ASPC126-B	Anti-PRNP Antibody (mAb 132), Biotin	Mouse IgG1, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC126

Anti-PRNP Antibody (mAb 132)

Mouse IgG1, Kappa

None

$460

In stock

Add

ASPC126-P

Anti-PRNP Antibody (mAb 132), PE

Mouse IgG1, Kappa

$1,180

2-3 weeks

Add

ASPC126-A

Anti-PRNP Antibody (mAb 132), APC

Mouse IgG1, Kappa

APC

$980

2-3 weeks

Add

ASPC126-H

Anti-PRNP Antibody (mAb 132), HRP

Mouse IgG1, Kappa

HRP

$600

2-3 weeks

Add

ASPC126-B

Anti-PRNP Antibody (mAb 132), Biotin

Mouse IgG1, Kappa

Biotin

$680

2-3 weeks

Add

Anti-PRNP Monoclonal Antibody (mAb 132)
- Product Description:
  
  mAb 132 is a monoclonal antibody that specifically recognizes the mouse prion protein (PrP).
  
  Applications:
  
  Surface Plasmon Resonance, Enzyme-Linked Immunosorbent Assay, Western Blot, Flow Cytometry, Immunofluorescence
  
  Source:
  
  Mouse
  
  Target:
  
  PRNP
  
  Target Species:
  
  Mouse
  
  Specificity:
  
  Mouse prion protein
  
  Immunogen:
  
  Mouse PRNP protein
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  mAb 132
  
  Isotype:
  
  Mouse IgG1, Kappa
  
  Purification:
  
  The antibody was purified by Protein A.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for customized product form or formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-PRNP Monoclonal Antibody (mAb 132) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

Prnp

Protein Name

Major prion protein

Introduction

Enables several functions, including amyloid-beta binding activity; aspartic-type endopeptidase inhibitor activity; and cupric ion binding activity. Involved in several processes, including negative regulation of macromolecule metabolic process; positive regulation of protein localization to membrane; and positive regulation of protein phosphorylation. Acts upstream of or within several processes, including negative regulation of apoptotic process; regulation of potassium ion transmembrane transport; and response to oxidative stress. Located in several cellular components, including Golgi apparatus; membrane raft; and terminal bouton. Colocalizes with dendrite. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ.

Alternative Names

Major prion protein; PrP; PrPC; Sinc; CD230; PrPSc; Prn-i; Prn-p; Prnp; prP27-30; prP33-35C

Gene ID

19122

UniProt

P04925

Related Disease

Degenerative neurological diseases

Subcellular Location

Cell membrane; Golgi apparatus

Tissue Specificity

Highly expressed in the brain, lung, kidney and heart. Expressed at low levels in the liver and spleen.