Anti-PLD4 Monoclonal Antibody (14H2)

Subcat	Description	Isotype	Conjugate	Price	Availability
ASPC291	Anti-PLD4 Antibody (14H2)	Mouse IgG1, Kappa	None	$460	In stock	Add
ASPC291-P	Anti-PLD4 Antibody (14H2), PE	Mouse IgG1, Kappa	PE	$1,180	2-3 weeks	Add
ASPC291-A	Anti-PLD4 Antibody (14H2), APC	Mouse IgG1, Kappa	APC	$980	2-3 weeks	Add
ASPC291-H	Anti-PLD4 Antibody (14H2), HRP	Mouse IgG1, Kappa	HRP	$600	2-3 weeks	Add
ASPC291-B	Anti-PLD4 Antibody (14H2), Biotin	Mouse IgG1, Kappa	Biotin	$680	2-3 weeks	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Availability

Quantity

ASPC291

Anti-PLD4 Antibody (14H2)

Mouse IgG1, Kappa

None

$460

In stock

Add

ASPC291-P

Anti-PLD4 Antibody (14H2), PE

Mouse IgG1, Kappa

$1,180

2-3 weeks

Add

ASPC291-A

Anti-PLD4 Antibody (14H2), APC

Mouse IgG1, Kappa

APC

$980

2-3 weeks

Add

ASPC291-H

Anti-PLD4 Antibody (14H2), HRP

Mouse IgG1, Kappa

HRP

$600

2-3 weeks

Add

ASPC291-B

Anti-PLD4 Antibody (14H2), Biotin

Mouse IgG1, Kappa

Biotin

$680

2-3 weeks

Add

Anti-PLD4 Monoclonal Antibody (14H2)
- Product Description:
  
  The Anti-PLD4 antibody is a mouse monoclonal antibody recommended for use in flow cytometry and other applications. This antibody specifically targets PLD4 and demonstrates reactivity with cynomolgus monkey.
  
  Applications:
  
  Flow Cytometry
  
  Target:
  
  PLD4
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human PLD4.
  
  Immunogen:
  
  Recombinant Phospholipase D Family Member 4
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  14H2
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-PLD4 Monoclonal Antibody (14H2) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

PLD4

Protein Name

5'-3' exonuclease PLD4

Introduction

Predicted to enable single-stranded DNA 5'-3' DNA exonuclease activity. Predicted to be involved in hematopoietic progenitor cell differentiation; phagocytosis; and regulation of cytokine production involved in inflammatory response. Predicted to act upstream of or within establishment of localization in cell. Predicted to be located in early endosome and endoplasmic reticulum membrane. Predicted to be active in several cellular components, including endoplasmic reticulum; phagocytic vesicle; and trans-Golgi network membrane.

Alternative Names

PLD4; phospholipase D family, member 4; C14orf175; phospholipase D4; PLD 4; choline phosphatase 4; phosphatidylcholine-hydrolyzing phospholipase D4

Gene ID

122618

UniProt

Q96BZ4

Subcellular Location

Endoplasmic reticulum membrane

Cell Line Specificity

Group enriched

Function

5'->3' DNA exonuclease which digests single-stranded DNA (ssDNA). Regulates inflammatory cytokine responses via the degradation of nucleic acids, by reducing the concentration of ssDNA able to stimulate TLR9, a nucleotide-sensing receptor. Involved in phagocytosis of activated microglia.

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