Anti-PLAU Monoclonal Antibody - Amerigo Scientific

Subcat	Description	Isotype	Conjugate	Price
ASPC1321	Anti-PLAU Antibody	Mouse IgG1, Kappa	None	$460	Add
ASPC1321-A	Anti-PLAU Antibody, APC	Mouse IgG1, Kappa	APC	$980	Add
ASPC1321-B	Anti-PLAU Antibody, Biotin	Mouse IgG1, Kappa	Biotin	$680	Add
ASPC1321-H	Anti-PLAU Antibody, HRP	Mouse IgG1, Kappa	HRP	$600	Add
ASPC1321-P	Anti-PLAU Antibody, PE	Mouse IgG1, Kappa	PE	$1,180	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC1321

Anti-PLAU Antibody

Mouse IgG1, Kappa

None

$460

Add

ASPC1321-A

Anti-PLAU Antibody, APC

Mouse IgG1, Kappa

APC

$980

Add

ASPC1321-B

Anti-PLAU Antibody, Biotin

Mouse IgG1, Kappa

Biotin

$680

Add

ASPC1321-H

Anti-PLAU Antibody, HRP

Mouse IgG1, Kappa

HRP

$600

Add

ASPC1321-P

Anti-PLAU Antibody, PE

Mouse IgG1, Kappa

$1,180

Add

Anti-PLAU Monoclonal Antibody
- Product Description:
  
  The Anti-PLAU antibody is a mouse monoclonal antibody recommended for use in western blot, blocking and other applications. This antibody specifically targets PLAU and demonstrates reactivity with human.
  
  Applications:
  
  Western Blot, Blocking
  
  Target:
  
  PLAU
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with Human PLAU.
  
  Immunogen:
  
  Human PLAU
  
  Clonality:
  
  Monoclonal
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-PLAU Monoclonal Antibody Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

PLAU

Protein Name

Urokinase-type plasminogen activator

Introduction

This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimers disease and also with decreased affinity for fibrin-binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor.

Alternative Names

PLAU; plasminogen activator; urokinase; ATF; QPD; UPA; URK; u-PA

Gene ID

5328

UniProt

P00749

Related Disease

Quebec platelet disorder (QPD)

Subcellular Location

Secreted

Tissue Specificity

Expressed in the prostate gland and prostate cancers.

Cell Line Specificity

Cancer enhanced

Function

Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin.

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