Anti-PLAU Monoclonal Antibody (4A5)

Subcat	Description	Isotype	Conjugate	Price
ASPC412	Anti-PLAU Antibody (4A5)	Human IgG1, Kappa	None	$460	Add
ASPC412-P	Anti-PLAU Antibody (4A5), PE	Human IgG1, Kappa	PE	$1,180	Add
ASPC412-A	Anti-PLAU Antibody (4A5), APC	Human IgG1, Kappa	APC	$980	Add
ASPC412-H	Anti-PLAU Antibody (4A5), HRP	Human IgG1, Kappa	HRP	$600	Add
ASPC412-B	Anti-PLAU Antibody (4A5), Biotin	Human IgG1, Kappa	Biotin	$680	Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASPC412

Anti-PLAU Antibody (4A5)

Human IgG1, Kappa

None

$460

Add

ASPC412-P

Anti-PLAU Antibody (4A5), PE

Human IgG1, Kappa

$1,180

Add

ASPC412-A

Anti-PLAU Antibody (4A5), APC

Human IgG1, Kappa

APC

$980

Add

ASPC412-H

Anti-PLAU Antibody (4A5), HRP

Human IgG1, Kappa

HRP

$600

Add

ASPC412-B

Anti-PLAU Antibody (4A5), Biotin

Human IgG1, Kappa

Biotin

$680

Add

Anti-PLAU Monoclonal Antibody (4A5)
- Product Description:
  
  The Anti-PLAU antibody is a human monoclonal antibody recommended for use in ELISA, functional assay, western blot and other applications. This antibody specifically targets PLAU and demonstrates reactivity with human.
  
  Applications:
  
  Functional Assay, Western Blot
  
  Target:
  
  PLAU
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human uPA (urokinase-type plasminogen activator).
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  4A5
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Aggregation:
  
  <5% as determined by SEC
  
  Form:
  
  Liquid
  
  Endotoxin:
  
  Please contact us for more information.
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  BSA and Azide free.
  
  Stabilizer:
  
  None
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be store at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-PLAU Monoclonal Antibody (4A5) Applications
- Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Gene Symbol

PLAU

Protein Name

Urokinase-type plasminogen activator

Introduction

This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Alternative Names

PLAU; plasminogen activator, urokinase; ATF; QPD; UPA; URK; u-PA; BDPLT5

Gene ID

5328

UniProt

P00749

Related Disease

Quebec platelet disorder (QPD)

Subcellular Location

Secreted

Tissue Specificity

Expressed in the prostate gland and prostate cancers.

Cell Line Specificity

Cancer enhanced

Function

Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin.

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