Anti-Pdpn Monoclonal Antibody (PMab-1)

Anti-Pdpn Monoclonal Antibody (PMab-1)

Cat No: ASPF131

Summary
Host Species:
Mouse
Species Reactivity:
Mouse
Applications:
Flow Cytometry, Western Blot, Blocking, Enzyme-linked Immunosorbent Assay, Flow Cytometry, Immunohistochemistry
Clone ID:
PMab-1
Clonality:
Monoclonal

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Product Information
Subcat Description Isotype Antibody Modification Conjugate Size Price Quantity
ASPF131 Anti-Pdpn Antibody (PMab-1) Mouse IgG1 None $460
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ASPF131-A Anti-Pdpn Antibody (PMab-1), APC Mouse IgG1 APC $980
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ASPF131-B Anti-Pdpn Antibody (PMab-1), Biotin Mouse IgG1 Biotin $680
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ASPF131-H Anti-Pdpn Antibody (PMab-1), HRP Mouse IgG1 HRP $600
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ASPF131-P Anti-Pdpn Antibody (PMab-1), PE Mouse IgG1 PE $1,180
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Custom Antibody We can also offer conjugation antibodies (Alexa Fluor, Cy, APC, etc.) and other format antibodies (low endotoxin, Fab, scFv, etc.)

  • Anti-Pdpn Monoclonal Antibody (PMab-1)
    • Product Description:
      This product is a mouse monoclonal antibody (clone PMab-1) that binds mouse podoplanin (Pdpn) within the platelet-aggregation-stimulating domain (aa 38-51), is validated in flow cytometry, Western blot, ELISA and immunohistochemistry, is azide-free, and is employed in tumor-lymphangiogenesis and fibrosis research.
      Applications:
      Flow Cytometry, Western Blot, Blocking, Enzyme-linked Immunosorbent Assay, Flow Cytometry, Immunohistochemistry
      Source:
      Mouse
      Target:
      Pdpn
      Target Species:
      Mouse
      Specificity:
      This antibody reacts with Mouse Pdpn.
      Immunogen:
      14-residue synthetic peptide mpp3851, which corresponds to amino acids 38-51 (GDGMVPPGIEDKIT) of the platelet-aggregation-stimulating (PLAG) domain of mouse podoplanin.
      Epitope:
      AA 38-51 (GDGMVPPGIEDKIT)
      Clonality:
      Monoclonal
      Clone ID:
      PMab-1
      Purification:
      The antibody was purified by affinity chromatography.
      Purity:
      >95% as determined by SDS-PAGE
      Aggregation:
      <5% as determined by SEC
      Form:
      Liquid
      Endotoxin:
      Please contact us for more information.
      Formulation:
      Contact us for custom product formulation.
      Preservative:
      BSA and Azide free.
      Stabilizer:
      None
      Shipping:
      Shipped at 4°C.
      Storage:
      This antibody can be stored at 2°C-8°C for one month. Upon delivery aliquot. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
  • Anti-Pdpn Monoclonal Antibody (PMab-1) Applications
    • Note:
      Optimal dilutions/concentrations should be determined by the end user.
Gene Symbol
Pdpn
Protein Name
Podoplanin
Introduction
This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alternative Names
Podoplanin; Lung Type I Cell Membrane Associated Glycoprotein; Glycoprotein 36; PA2.26 Antigen; T1-Alpha; AGGRUS; GP36; T1A; Lung Type-I Cell Membrane-Associated Glycoprotein (T1A-2); Glycoprotein, 36-KD; HT1alpha-1
Gene ID
UniProt
Related Disease
Tumor metastasis
Subcellular Location
Cell junction, Cell membrane, Cell projection, Cytoplasm, Membrane
Tissue Specificity
Tissue enhanced (Placenta)
Cell Line Specificity
Cancer enhanced (Testis cancer, Thyroid cancer)
Function
Podoplanin, a transmembrane glycoprotein involved in cell migration and lymphangiogenesis.
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