Anti-PDIA2 Monoclonal Antibody (C-7F2)

Subcat	Description	Isotype	Antibody Modification	Conjugate	Size	Price	Quantity
ASZ1C1476	Anti-PDIA2 Antibody (C-7F2)	Mouse IgG		None		$460		Add

Subcat

Description

Isotype

Antibody Modification

Conjugate

Size

Price

Quantity

ASZ1C1476

Anti-PDIA2 Antibody (C-7F2)

Mouse IgG

None

$460

Add

Anti-PDIA2 Monoclonal Antibody (C-7F2)
- Product Description:
  
  The Anti-PDIA2 antibody is a mouse monoclonal antibody recommended for immunohistochemistry, immunocytochemistry, western blot, immunoprecipitation and other applications. This antibody specifically targets human PDIA2.
  
  Applications:
  
  Immunohistochemistry, Immunocytochemistry, Western Blot, Immunoprecipitation
  
  Source:
  
  Mouse
  
  Target:
  
  PDIA2
  
  Target Species:
  
  Human
  
  Specificity:
  
  This antibody reacts with human Protein Disulfide Isomerase Family A Member 2 (PDIA2).
  
  Clonality:
  
  Monoclonal
  
  Clone ID:
  
  C-7F2
  
  Purification:
  
  The antibody was purified by affinity chromatography.
  
  Purity:
  
  >95% as determined by SDS-PAGE
  
  Concentration:
  
  1 mg/mL
  
  Form:
  
  Liquid
  
  Formulation:
  
  Contact us for custom product formulation.
  
  Preservative:
  
  0.02% sodium azide
  
  Shipping:
  
  Shipped at 4°C.
  
  Storage:
  
  This antibody can be stored at 2°C-8°C for one month. For longer storage, store at -20°C. Avoid repeated freeze-thaw cycles.
Anti-PDIA2 Monoclonal Antibody (C-7F2) Applications
- Recommended Dilution:
  
  Western Blot: 1:500-1:5000
  Immunohistochemistry: 1:50-1:200
  Immunocytochemistry: 1:50-1:200
  
  Note:
  
  Optimal dilutions/concentrations should be determined by the end user.

Protein Name

Protein disulfide-isomerase A2

Introduction

This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, two TRX-like domains and a C-terminal ER-retention sequence. The protein plays a role in the folding of nascent proteins in the endoplasmic reticulum by forming disulfide bonds through its thiol isomerase, oxidase, and reductase activity. The encoded protein also possesses estradiol-binding activity and can modulate intracellular estradiol levels.

Alternative Names

PDA2; PDI; PDIP; PDIR

Gene ID

64714

UniProt

Q13087

Subcellular Location

Endoplasmic reticulum lumen

Tissue Specificity

Highly expressed in pancreas (at protein level).

Cell Line Specificity

Cancer enhanced

Function

Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins.

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